Publications by authors named "Marissa McDaniel"
Commun Med (Lond)
October 2024
Article Synopsis
- Questions remain about the role of race and geographic ancestry in biomedical research, particularly how they can enhance matching algorithms for human leukocyte antigen (HLA) in stem cell transplants from donor registries.
- Analysis of self-reported racial and ancestral data from over 100,000 U.S. bone marrow donors shows discrepancies among these measures; using both race and geographic ancestry together yields the best fit for HLA genetic ancestry.
- The findings suggest that while direct matching for transplants doesn't use these data, incorporating both race and geographic ancestry is valuable for improving predictions of HLA compatibility in donor registries.
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