Publications by authors named "Marissa Bt Madzlan Kushairi"
Evaluating the outcome of a bundle with 11 components and the INICC multidimensional approach in decreasing rates of central line-associated bloodstream infections across nine Asian countries.
J Vasc Access
March 2024
Article Synopsis
- Central line-associated bloodstream infection (CLABSI) rates in Latin American ICUs are significantly higher than in high-income countries, prompting a need for intervention.
- The INICC multidimensional approach, which includes an 11-component bundle, was implemented across 122 ICUs in nine Asian countries, resulting in a substantial decrease in CLABSI rates from 16.64 to 2.18 over 29 months.
- The intervention not only reduced CLABSI rates by 87% but also significantly lowered the all-cause in-ICU mortality rate from 13.23% to 10.96%.
Multinational prospective cohort study of incidence and risk factors for central line-associated bloodstream infections over 18 years in 281 ICUs of 9 Asian countries.
J Vasc Access
September 2024
Article Synopsis
- The study aimed to analyze the rates and risk factors of central line-associated bloodstream infections (CLABSI) across 281 ICUs in 9 Asian countries from 2004 to 2022.
- Out of 150,142 patients, a total of 1514 CLABSIs were recorded, with an overall infection rate of 5.08 per 1000 central line days, highest in femoral and temporary hemodialysis catheters.
- Key risk factors for CLABSI included longer hospital stays before infection, tracheostomy use, hospitalization type, and facility ownership, particularly in publicly-owned and lower-middle-income country facilities.
Multinational prospective cohort study over 18 years of the risk factors for ventilator-associated pneumonia in 9 Asian countries: INICC findings.
Am J Infect Control
July 2023
Background: Ventilator associated pneumonia (VAP) rates in Asia are several times above those of US. The objective of this study is to identify VAP risk factors.
Methods: We conducted a prospective cohort study, between March 27, 2004 and November 2, 2022, in 279 ICUs of 95 hospitals in 44 cities in 9 Asian countries (China, India, Malaysia, Mongolia, Nepal, Pakistan, Philippines, Sri Lanka, Thailand, Vietnam).
Objective: To identify risk factors for mortality in intensive care units (ICUs) in Asia.
Design: Prospective cohort study.
Setting: The study included 317 ICUs of 96 hospitals in 44 cities in 9 countries of Asia: China, India, Malaysia, Mongolia, Nepal, Pakistan, Philippines, Sri Lanka, Thailand, and Vietnam.