Comparison of traditional regression modeling vs. AI modeling for the prediction of dental caries: a secondary data analysis.

Introduction: There are substantial gaps in our understanding of dental caries in primary and permanent dentition and various predictors using newer modeling methods such as Machine Learning (ML) algorithms and Artificial Intelligence (AI). The objective of this study is to compare the accuracy, precision, and differences between the caries predictive capability of AI vs. traditional multivariable regression techniques.

Enhancing an AI-Empowered Periodontal CDSS and Comparing with Traditional Perio-risk Assessment Tools.

Periodontal disease (PD) is one of the most prevalent dental diseases. Fortunately, it can be prevented if identified early, especially for high-risk patients. Dental electronic health records (EHRs) could help develop a data-driven personalized prediction model using advanced machine learning development of clinical decision support system (CDSS) as in our Phase I, II AMIA-AI showcase.

Emotional distress and risk of dental caries: Evaluating effect modification by chronic conditions among low-income African American caregivers in Detroit, Michigan.

Background/aim: Limited research has been conducted regarding the association between mental illness and dental caries. We studied the impact of emotional distress on current and new dental caries among low-income African-American caregivers in Detroit, Michigan and if this association was mediated by poor oral hygiene and sugar consumption and modified by a chronic health condition.

Methods: Data came from Detroit Dental Health Project, a prospective cohort study of low-income African American caregivers and their children.

Developing Automated Computer Algorithms to Phenotype Periodontal Disease Diagnoses in Electronic Dental Records.

Objective: Our objective was to phenotype periodontal disease (PD) diagnoses from three different sections (diagnosis codes, clinical notes, and periodontal charting) of the electronic dental records (EDR) by developing two automated computer algorithms.

Methods: We conducted a retrospective study using EDR data of patients ( = 27,138) who received care at Temple University Maurice H. Kornberg School of Dentistry from January 1, 2017 to August 31, 2021.

Developing and testing a prediction model for periodontal disease using machine learning and big electronic dental record data.

Despite advances in periodontal disease (PD) research and periodontal treatments, 42% of the US population suffer from periodontitis. PD can be prevented if high-risk patients are identified early to provide preventive care. Prediction models can help assess risk for PD before initiation and progression; nevertheless, utilization of existing PD prediction models is seldom because of their suboptimal performance.

Limited quality evidence suggests children and adolescents with down syndrome have lower prevalence of dental caries compared to non-syndromic children.

Article Title And Bibliographic Information: Silva MCPMD, Lyra MCA, Almeida HCR, Alencar Filho AV, Heimer MV, Rosenblatt A. Caries experience in children and adolescents with Down Syndrome: A systematic review and meta-analysis. Arch Oral Biol.

Molecular docking studies, in-silico ADMET predictions and synthesis of novel PEGA-nucleosides as antimicrobial agents targeting class B1 metallo-β-lactamases.

Class B1 metallo-β-lactamases (MBLs) are metalloenzymes found in drug resistant bacteria. The enzyme requires zinc ions, along with conserved amino acid coordination for nucleophilic attack of the lactam ring to induce hydrolysis and inactivation of β-lactam and some carbapenem antibiotics. To this date there are no clinically relevant class B1 MBL inhibitors, however L-captopril has shown significant results against NDM-1, the most difficult MBL to inhibit.

Mitigating saliva aerosol contamination in a dental school clinic.

Background: Transmission of COVID-19 via salivary aerosol particles generated when using handpieces or ultrasonic scalers is a major concern during the COVID-19 pandemic. The aim of this study was to assess the spread of dental aerosols on patients and dental providers during aerosol-generating dental procedures.

Methods: This pilot study was conducted with one volunteer.

An innovative approach to assess comprehensive care: Temple University's patient wellness report.

Purpose: The transition from a paper-based to an all-electronic patient health record took a major step forward in 2018, with the implementation of an electronic health record that supports the School's patient-centered comprehensive care model and facilitates outcomes assessment. The Patient Wellness Report (PWR) summarizes findings of the patient assessment, and it does so automatically by locating data already entered in axiUm forms. This study aimed to describe the PWR implementation procedures and to examine outcomes and characteristics among patients with completed treatment plans during an 18-month period.

Randomised clinical trial of a motivational interviewing intervention to improve oral health education amongst older adults in Philadelphia: 12-month evaluation of non-clinical outcomes.

Objectives: We conducted a trial to assess the treatment fidelity of an individual-based oral health education intervention utilising motivational interviewing (MI) techniques and its efficacy when compared to a group-based traditional oral health education intervention (TOHE) and a standard of care group (SC) in a sample from Philadelphia during a 12-month follow-up.

Background: There is lack of information on how different types of oral health educational interventions affect older adults on non-clinical outcomes including changes in oral health-related quality of life (OHRQoL), oral health self-efficacy (SE) and oral health knowledge (OHK).

Materials And Methods: One hundred and eighty patients were randomly allocated to TOHE, MI and SC groups.

ICDAS Is Widely Used as Standardized and Reliable Caries Detection Criteria, but Its Reporting Varies Widely.

Article Title And Bibliographic Information: Caries reporting in studies that used the International Caries Detection and Assessment System: A scoping review. ElSalhy M, Ali U, Lai H, Flores-Mir C, Amin M. Community Dent Oral Epidemiol 2019; 47(1): 92-102.

An innovative individual-level caries severity and progression indicator among children.

Objective: To propose an individual-level indicator of caries severity based on the maximum score generated using the international caries detection and assessment system (ICDAS) and test validity of this individual-level indicator by assessing differences between this proposed indicator and the traditional decayed, missing, and filled surfaces (DMFS or dmfs for primary teeth) index.

Methods: Data on caries severity were collected using a representative sample of children from Detroit, Michigan, aged less than 6 years (N = 749) examined in 2002-2003 (W1) and 2004-2005 (W2). For each wave, each child was assigned to six caries severity groups based on the maximum ICDAS scores.

Chronic Stress and Unhealthy Dietary Behaviors among Low-Income African-American Female Caregivers.

Background: Chronic stress increases the risk of excess intake of calorie-dense foods. Low-income minority caregivers in the United States are cumulatively exposed to stressors and unhealthy foods, but evidence of this association is limited in this population group. The objective of the current study was to assess the association between chronic stress and unhealthy dietary behaviors among low-income African-American caregivers in Detroit, Michigan.

Supragingival mycobiome and inter-kingdom interactions in dental caries.

: Recent studies have reveled the presence of a complex fungal community (mycobiome) in the oral cavity. However, the role of oral mycobiome in dental caries and its interaction with caries-associated bacteria is not yet clear. : Whole-mouth supragingival plaque samples from 30 children (6-10 years old) with no caries, early caries, or advanced caries were sequenced for internal transcribed spacer 2 (ITS-2).

Estimating a Dynamic Effect of Soda Intake on Pediatric Dental Caries Using Targeted Maximum Likelihood Estimation Method.

An effect of soda intake on dental caries in young children (birth to 5 years) may vary over time. Estimating a dynamic effect may be challenging due to time-varying confounding and loss to follow-up. The purpose of this paper is to demonstrate utility of targeted maximum likelihood estimation (TMLE) method in addressing longitudinal data analysis challenges and estimating a dynamic effect of soda intake on pediatric caries.

Motivational interviewing and oral health education: Experiences from a sample of elderly individuals in North and Northeast Philadelphia.

Background: Health education has a focus on knowledge dissemination and advice giving, which seldom translates into behavioral changes. Motivational interviewing (MI) has potential for helping elderly patients. However, most oral health studies conducted to date have excluded older individuals, and the outcomes examined have been exclusively clinical.

Metagenome sequencing-based strain-level and functional characterization of supragingival microbiome associated with dental caries in children.

Studies of the microbiome associated with dental caries have largely relied on 16S rRNA sequence analysis, which is associated with PCR biases, low taxonomic resolution, and inability to accurately study functions. Here, we employed whole metagenome shotgun sequencing, coupled with high-resolution analysis algorithm, to analyze supragingival microbiomes from 30 children with or without dental caries. A total of 726 bacterial strains belonging to 406 species, in addition to 34 bacteriophages were identified.

Limited-Quality Evidence Suggests That Early Caries Experience at Age 6 years May Predict Low Oral Health-Related Quality of Life at Age 10 years.

Article Title And Bibliographic Information: Early Caries Predicts Low Oral Health-Related Quality of Life at a Later Age. Kragt L, van der Tas JT, Moll HA, Elfrink ME, Jaddoe VW, Wolvius EB, Ongkosuwito EM. Caries Res.

Dental Students' Attitudes Toward Tobacco Cessation in the Dental Setting: A Systematic Review.

Many dental schools have integrated tobacco cessation into their predoctoral curricula. However, dental students' perceptions should be taken into consideration when designing those curricula. The aim of this study was to systematically review the published literature on dental students' attitudes and perceptions regarding tobacco cessation.

Identifying Noncognitive Skills That Contribute to Dental Students' Success: Dental Faculty Perspectives.

The aims of this study were to identify noncognitive factors that dental faculty members perceived to contribute to dental students' success and to assess dental faculty members' ratings of the relative importance of these factors to academic performance, clinical performance, and overall success. Out of 184 eligible faculty members at one U.S.

Red fluorescence of dental plaque in children -A cross-sectional study.

Objectives: The relation between the presence of red fluorescent plaque and the caries status in children was studied. In addition, the microbial composition of dental plaque from sites with red fluorescent plaque (RFP) and from sites with no red fluorescent plaque (NFP) was assessed.

Methods: Fluorescence photographs were taken from fifty children (6-14 years old) with overnight plaque.

The Public Health Reach of High Fluoride Vehicles: Examples of Innovative Approaches.

Fluorides and sealants have been shown to reduce caries in populations, making fluoride interventions a large part of the dental public health effort. Although public health programs have traditionally focused on fluoride vehicles delivering less than 1,000 ppm of fluoride, more recent efforts have shifted toward the use of high fluoride vehicles such as varnishes and prescription toothpastes. In the USA, states are developing innovative strategies to increase access to dental services by using primary care medical providers to deliver early preventive services as part of well-child care visits.

Baseline Caries Risk Assessment Using CAMBRA May Predict Caries Only in High and Extreme Caries Risk Groups.

Article Title And Bibliographic Information: Baseline caries risk assessment as a predictor of caries incidence. Chaffee BW, Cheng J, Featherstone JD.J Dent 2015;43(5):518-24.

Frailty, Frailty Components, and Oral Health: A Systematic Review.

A systematic review was conducted to assess the relationship between frailty or one of its components and poor oral health. A search strategy was developed to identify articles related to the research question in the PubMed, EMBASE, Cochrane, LILACS, and SciELO databases that were published in English, Spanish, or Brazilian Portuguese from 1991 to July 2013. Thirty-five studies were identified, and 12 met the inclusion criteria, seven of which were cross-sectional and five were cohort studies.