Publications by authors named "Marisol Olivares-Arevalo"
Genome-Wide Association Study Identifies a Functional Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease.
Paola León-Mimila Hugo Villamil-Ramírez Luis R Macías-Kauffer Leonor Jacobo-Albavera Blanca E López-Contreras Marisol Olivares-Arevalo
Arterioscler Thromb Vasc Biol
September 2021
Article Synopsis
- A study was conducted to find genetic variants linked to low HDL-C levels in Mexicans, identifying four significant loci, including a notable variant in the SIDT2 gene.
- The SIDT2/Val636Ile variant is more common in Native American populations and is associated with improved cholesterol levels and a lower risk of premature coronary artery disease.
- The findings suggest that SIDT2 plays a crucial role in cholesterol metabolism, providing new insights into the genetics of HDL-C and its relationship to heart health in the Mexican population.