Publications by authors named "Mariska Q N Hackert"

Article Synopsis
  • The study investigates real-world treatment strategies for neutropenia in patients taking palbociclib, focusing on their impact on progression-free survival (PFS) against outcomes in clinical trials.
  • Data from 229 patients with HR-positive, HER2-negative metastatic breast cancer were analyzed, revealing different treatment modifications compared to the PALOMA-3 clinical trial, but no significant effect on PFS.
  • Patients deemed ineligible for the PALOMA-3 trial had shorter PFS, emphasizing that real-world outcomes may differ from those observed in clinical trials.
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Introduction: Within the value-based healthcare framework, outcome data can be used to inform patients about (treatment) options, and empower them to make shared decisions with their health care professional. To facilitate shared decision-making (SDM) supported by outcome data, a multicomponent intervention has been designed, including patient decision aids on the organisation of post-treatment surveillance (breast cancer); discharge location (stroke) and treatment modality (advanced kidney disease), and training on SDM for health care professionals. The SHared decision-making supported by OUTcome information (SHOUT) study will examine the effectiveness of the intervention and its implementation in clinical practice.

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Background: Valid measures of the well-being of older people are important for the evaluation of health and social care services. The nine-item Well-being of Older People measure (WOOP) was based on a novel framework derived from a recent Q-methodology study, and was developed to capture a comprehensive set of well-being domains relevant to older people, as identified by themselves. This study introduces the WOOP and describes the qualitative assessment of its feasibility and content validity.

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Article Synopsis
  • There is a new measure called the Well-being of Older People (WOOP) that assesses what older individuals find important for their well-being.
  • The study tested the WOOP's reliability and validity using data from over 1,100 people aged 65+ in the Netherlands, finding strong connections with established measures of health and well-being.
  • Although initial results are promising, further validation in different health and social care environments is needed before using WOOP in economic evaluations, as well as determining its utility weights.
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Population ageing and restricted budgets result in the need for an efficient allocation of scarce resources in care services for older people. As these services tend to address more than only health, diverse wellbeing measures have been developed to assess their benefits in economic evaluations. These measures are grounded in research on wellbeing of older people and its determinants.

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Purpose: The ICEpop CAPability measure for Older people (ICECAP-O) is intended for use in economic evaluations of care services for older people. Although studies support the validity of the ICECAP-O, it does not directly ask older people about their health. This raises questions about its ability to capture health indirectly.

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Background: Limited health care budgets and population aging result in a need to compare care services on their benefits and costs. Because services for older people often aim to improve multiple life aspects, valid measures are needed to examine their benefits on individuals' health and well-being simultaneously. Two measures may meet this end: the Adult Social Care Outcomes Toolkit (ASCOT) and the ICEpop CAPability measure for Older people (ICECAP-O).

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