Optimised Workflows for Profiling the Metabolic Fluxes in Suspension vs. Adherent Cancer Cells via Seahorse Technology.

Oxidative phosphorylation and glycolysis are the main ATP-generating pathways in cell metabolism. The balance between these two pathways is frequently altered to carry out cell-specific activities in response to stimuli involving activation, proliferation, or differentiation. Despite being a useful tool for researching metabolic profiles in real time in relatively small numbers of cancer cells, the main Agilent Seahorse XF Pro Analyzer (Agilent Technologies, Santa Clara, CA, USA) guideline is currently not fully detailed in the distinction between suspensions vs.

Extraction Optimization of L. Wood Chips: A Comparative Study between Full Factorial Design (FFD) and Artificial Neural Network (ANN).

From a circular bio-economy perspective, biomass valorization requires the implementation of increasingly efficient extraction techniques to ensure the environmental and economic sustainability of biorefining processes. This research focuses on optimizing the specialized metabolite extraction of Turkey oak chips from L. by applying a 3 levels Full Factorial Design (FFD).

Synergic Role of Dietary Bioactive Compounds in Breast Cancer Chemoprevention and Combination Therapies.

Breast cancer is the most common tumor in women. Chemotherapy is the gold standard for cancer treatment; however, severe side effects and tumor resistance are the major obstacles to chemotherapy success. Numerous dietary components and phytochemicals have been found to inhibit the molecular and signaling pathways associated with different stages of breast cancer development.

The Killer's Web: Interconnection between Inflammation, Epigenetics and Nutrition in Cancer.

Inflammation is a key contributor to both the initiation and progression of tumors, and it can be triggered by genetic instability within tumors, as well as by lifestyle and dietary factors. The inflammatory response plays a critical role in the genetic and epigenetic reprogramming of tumor cells, as well as in the cells that comprise the tumor microenvironment. Cells in the microenvironment acquire a phenotype that promotes immune evasion, progression, and metastasis.

HS-SPME-GC-MS determination of the scent of taxa (fam. Orchidaceae) from Basilicata (Southern Italy).

The scent of species has been analyzed by using HS-SPME-GC-MS. The sample was collected in Basilicata (Southern Italy). Every species showed a different composition of the scent in the analyses we performed.

A potential host and virus targeting tool against COVID-19: Chemical characterization, antiviral, cytoprotective, antioxidant, respiratory smooth muscle relaxant effects of Paulownia tomentosa Steud.

COronaVIrus Disease 2019 (COVID-19) is a newly emerging infectious disease that spread across the world, caused by the novel coronavirus Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2). Despite the advancements in science that led to the creation of the vaccine, there is still an urgent need for new antiviral drugs effective against SARS-CoV-2. This study aimed to investigate the antiviral effect of Paulownia tomentosa Steud extract against SARS-CoV-2 and to evaluate its antioxidant properties, including respiratory smooth muscle relaxant effects.

The scent of orchids from Basilicata (Southern Italy).

The scent of species has been performed by using solid-phase microextraction- gas chromatography- mass spectrometry (SPME-GC-MS). The scent of showed the presence of 9-tricosene, 1-nonadecanol and heinecosane. The analysis of the scent of gave α-ionone as the main component.

Local Small Ruminant Grazing in the Monti Foy Area (Italy): The Relationship Between Grassland Biodiversity Maintenance and Added-Value Dairy Products.

The literature indicates that grazing small ruminants, when adequately managed, contributes to grassland biodiversity maintenance. On the other hand, milk and cheese from grazing animals show higher nutritional and aromatic quality than those from stall-fed animals. The relationship between the two issues has rarely been addressed.

Fragrance components of and collected at several sites in Italy and Germany.

The SPME-GC-MS analysis of the aroma components of subsp. , subsp. , var.

The composition of the aroma of orchids in Basilicata (Southern Italy).

The SPME-GC-MS analysis of the aroma components of subsp. and were reported. The relevant components of the scent of were α-amorphene, ethyl oleate, heneicosane, heptadecane, 2-heptadecanone, ethyl elaidate, pentadecane, octadecane, farnesylacetaldehyde, nonadecane, and ethyl stearate.

Aroma components of orchids.

The SPME-GC-MS analysis of the aroma components of , , and were reported. The main components found in were pentadecane, hexadecane, heptadecane and α-farnesene. The same compounds were found in the scent of .

Fragrance components of subsp. and collected in several sites in Italy.

subsp. sample collected at Grisolia showed as main components linalool (17.8%), benzyl benzoate (55.

High temperature treatment allows the detection of episesamin in paulownia wood extractives.

The composition and the relative variation of secondary metabolites of S. wood under thermal effect is a little explored area. Wood material was previously thermo-treated at 210 °C for 3 hours using a press vacuum technology.

Pollination features and floral volatiles of Gymnospermium scipetarum (Berberidaceae).

The discovery of few isolated populations of Gymnospermium scipetarum (since now considered as an amphi-Adriatic endemic) in the S-Apennines prompted to investigate, also for conservation purposes, some aspects of its reproductive biology. We aim: (1) to determine if insects play an important role in pollination; (2) to describe the pollinator community; (3) to detect floral scent composition. Experiments of insect exclusion were carried out in the field using 24 flowering individuals: one raceme was capped whereas the nearest one was used as control to ascertain differences in seed set.

Gallic acid as main product in the water extractives of ten.

The autoclave extraction of Hungarian oak (Quercus wood gave 5.3% extractives. The chloroform soluble fraction obtained from the extracts of allows to identify sesamin.

The Use of a Molybdenum Polyoxometalated Compound to Increase the Amount of Extractives from Wood Wastes.

The treatment of wood wastes of L., , , and S. in autoclave in the presence of micrometric crystals of H₃PMoO showed an impressive increase of the amount of extractives.

Chemical and biological evaluation of essential oil from (Falc.) Lipsch. from Garhwal Himalaya collected at different harvesting periods.

The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7).