Publications by authors named "Marisa Di Santo"

Article Synopsis
  • Ebstein's anomaly is a congenital heart condition involving tricuspid valve defects and associated complications, analyzed through data from 45 surgeries between 1990 and 2018, with a median age of 11.3 years for patients.
  • Surgical methods included valve repair (38%), cone reconstruction (42%), and replacement (19%), with additional surgeries needed for some patients, mainly for severe tricuspid insufficiency.
  • At a median follow-up of 6.5 years, the overall mortality rate was 11.5%, with favorable outcomes for cone reconstruction showing low mortality, less reoperation needed, and better medium-term durability compared to other techniques.
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Introduction: The COVID-19 pandemic has caused a global impact on public health services. Using new strategies through telehealth for the management of patients with congenital heart disease was the challenge.

Objective: To describe the experience in telecardiology, and the strategies implemented during the pandemic.

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In most cases, children with SARS-CoV-2 have a mild infection. However, very rarely, some children may develop a severe disease called multisystem inflammatory syndrome in children temporally associated with COVID-19 (MIS-C). Given its recent emergence, some aspects of its pathophysiology are still unknown.

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Background: Congenitally corrected transposition of the great arteries is a complex pathology characterised by atrioventricular and ventriculo-arterial discordance. Optimal surgical approaches are still a matter of debate.

Objective: To evaluate the outcomes of different surgical treatments in a single centre.

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Introduction: the incidence of invasive infections caused by pneumococcus (Streptococcus pneumoniae) has declined since generalized vaccination with pneumococcal conjugated vaccine, but it is still a prevalent pathogen in children. Amongst pneumococcal invasive infections, IE (infectious endocarditis) is rare, with an incidence between 1 and 7%.

Case Report: We describe the case of a previously healthy 4 year old boy, who had received one dose of 10-valent pneumococcal conjugate vaccine who presents with fever, a new heart murmur and heart failure.

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Takayasu arteritis is an idiopathic chronic granulomatous panarteritis predominantly affecting the aorta and its main branches. Although idiopathic, genetic contribution to disease susceptibility is being increasingly recognised. Rare in children, Takayasu arteritis is a worldwide disease with significant morbidity and mortality.

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A four year old patient with no medical history was admitted to our hospital's Emergency Department, suffering from edema and hypertension. During physical examination a low pulse was detected in the left arm and a lack of pulses in lower limbs, with a blood pressure difference greater than 10 mm Hg between both arms. An echocardiogram demonstrated severe aortic abdominal coarctation and ventricular dysfunction.

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Atrioventricular septal defect can present with one or more associated anomalies. Cor triatriatum (subdivided left atrium) and vascular rings are among the less frequent. We describe a two-month-old patient with these three cardiovascular anomalies.

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