Publications by authors named "Marisa Cristina Leite Santos Genelhu"
Alteration of the p63 protein expression has been associated with several human cancers including salivary gland tumors. We sought to assess the p63 expression in pleomorphic adenomas (PA) and carcinoma ex-pleomorphic adenomas (Ca ex-PA), since this protein has been related to myoepithelial phenotype and the biological behavior of cancer. Ten samples of PA and ten of Ca ex-PA were submitted to immunohistochemistry using a monoclonal anti-p63 antibody, clone 4A4.
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- The study examines how corrosion of orthodontic appliances can lead to nickel release, causing an allergic oral inflammatory response known as nickel-induced allergic contact stomatitis (NiACS).
- A retrospective analysis of 44 orthodontic patients revealed that younger patients, particularly females with prior allergic histories, are more likely to experience NiACS symptoms.
- The findings suggest that past allergic reactions are significant indicators of potential NiACS, highlighting the importance of documenting such histories in patients undergoing orthodontic treatment.