Publications by authors named "Mariona Morell"
Article Synopsis
- The study investigates the characteristics and quality of life (QoL) of patients diagnosed with childhood-onset craniopharyngioma, analyzing data from 66 patients treated between 2008 and 2022.
- Most patients were diagnosed at a young age (around 5 years) and faced long-term complications, including significant endocrine issues and visual deficits.
- QoL scores indicated that while patients rated their QoL higher than their parents did, factors like repeated surgeries, hypothalamic involvement, and the use of radiotherapy were found to negatively impact overall QoL.
Introduction: The assessment of quality of life (QoL) should be one of the main objectives in paediatric clinical trials. Even though researchers, regulators and advocates support the use of patient-reported outcomes (PROs), this has not been fully implemented. The aim of this study is to assess the measurement of QoL and the usage of PROs, palatability assessments and medication diaries in early-phase clinical trials for childhood and adolescent cancer.
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