Publications by authors named "Marion Geoffroy"
Article Synopsis
- A study was conducted to evaluate adherence to methotrexate (MTX) treatment in rheumatoid arthritis (RA) patients using a new urinary dosage method (METU) and compare it to traditional adherence measurements.* -
- The research involved 84 RA patients at Reims University Hospital, revealing that 91.7% were considered adherent according to METU, while indirect methods (Medication Possession Ratio and Compliance Questionnaire of Rheumatology) indicated lower adherence rates.* -
- The results suggest that indirect adherence assessments may not accurately reflect real-life adherence, highlighting the importance of using METU for better understanding treatment responses in RA patients.*
Background: The least significant change (LSC) threshold of 0.03 g/cm² is used to interpret bone mineral density (BMD) scans in the general population. Our working hypothesis was that the current LSC threshold would not be applicable in obese populations.
View Article and Find Full Text PDFBackground And Objectives: Methotrexate (MTX) is the first-line therapy for rheumatoid arthritis (RA). While therapeutic adherence is essential to successful management, no objective MTX assay is currently available. Using population pharmacokinetic modelling (PopPK), our objective was to describe the urinary MTX (MTXu) kinetics in treated patients and to evaluate its abilities to assess the MTX-adherence.
View Article and Find Full Text PDFMany studies have shown the effectiveness of platelet-rich plasma (PRP) in the treatment of knee osteoarthritis. We aimed to determine the factors associated with good or poor response to PRP injections in knee osteoarthritis. This was a prospective observational study.
View Article and Find Full Text PDFIntroduction: Bariatric surgery is used to treat severe obesity. We aimed to investigate the incidence of clinically significant bone mineral density (BMD) loss at 6 and 12 months after bariatric surgery.
Methods: Observational study performed in a specialized center for the treatment of obesity at the University Hospital of Reims, France.
Article Synopsis
- The study aimed to evaluate the effectiveness of a second needle biopsy in diagnosing spontaneous diskitis, particularly when initial blood cultures and biopsies returned negative results.
- Conducted between 2004 and 2014, the research included 63 patients, revealing that the first biopsy diagnosed 52% of cases, while the second biopsy confirmed diagnosis in 60% of those who underwent it.
- Findings indicated that prior antibiotic therapy was linked to negative results in the first biopsy, highlighting the potential importance of the timing and type of treatment received before the procedure.