Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases.

 Several authors have demonstrated the relationship between sudden sensorineural hearing loss (SNHL) and systemic autoimmune diseases (SAD). Immune-mediated SNHL can rarely present as unilateral sudden SNHL and manifests itself in the contralateral ear only after years. It presents clinical relevance for being one of the few SNHL that may be reversible given that early and appropriate treatment is applied.

Graphic angle measure as an electrocochleography evaluation parameter.

Unlabelled: To improve electrocochleography's diagnostic sensitivity in Meniére's disease - new assessment methods are being studied.

Aim: To determine whether or not graphic angle measurement is sensitive and specific to Menière's disease laboratorial diagnosis and if there is an increase in the electrocochleography's sensitivity and specificity when graphic angle measurements are associated with Summating Potential-Action Potential ratio (SP/AP ratio).

Methods: Electrocochleography's was used to analyze 71 ears from 55 subjects: 41 patients with clinical diagnosis of Menière's disease (MD group), and 14 healthy individuals as control (Group C).

Late auditory event-related evoked potential (P300) in Down's syndrome patients.

Unlabelled: Down syndrome is caused by a trisomy of chromosome 21 and is associated with central auditory processing deficit, learning disability and, probably, early-onset Alzheimer's disease.

Aim: To evaluate the latencies and amplitudes of evoked late auditory potential related to P300 events and their changes in young adults with Down's syndrome.

Materials And Methods: Prospective case study.

The outcome of patients with Ménières disease.

Unlabelled: Ménière;s disease is a frequent vestibular disease that occurs predominantly in the fourth decade of life. Diagnosis is mostly medical and is based on findings of vertigo, sensorineural hearing loss, tinnitus and aural fullness.

Aim: To study the clinical findings of Ménière;s disease: age, duration of vertigo, tinnitus, hearing loss and aural fullness, and unilateral or bilateral involvement.

Sigmoid sinus thrombosis associated to chronic otitis media.

Unlabelled: Otogenous lateral sinus thrombosis (OLST) is a rare disease and presents a controversial treatment.

Aim: Clinical aspects and treatment were reported based on our experience.

Methods: Retrospective study.

Optimizing the pharmacological component of integrated balance therapy.

Unlabelled: Drug treatment is an important option for the treatment of peripheral vestibular diseases.

Aim: To identify the drug component associated with optimal integrated balance therapy (IBT) for Ménières disease or other peripheral vestibular disorders.

Materials And Methods: Analysis of a series of patients with Ménières disease patients or patients with other peripheral vestibular disorders that received IBT involving either no medication or betahistine, cinnarizine, clonazepam, flunarizine or Ginkgo biloba during 120 days.

Mismatch negativity contribution in multiple sclerosis patients.

Unlabelled: Mismatch Negativity is a functional index of the supratemporal auditory cortex.

Aim: The aim of the present study on Mismatch Negativity (MMN) in multiple sclerosis (MS) patients was to evaluate if the MMN can be correlated with cognitive deficits assessed by the Paced Auditory Addition Task--PASAT.

Method: a clinical study in forty females and 20 males separated in two groups: control individuals and those with a definite diagnosis of MS underwent a duration and frequency MMN.

Clonazepam in the pharmacological treatment of vertigo and tinnitus.

We carried out a retrospective survey of 25 years of clinical experience with the use of clonazepam as a vestibular and tinnitus suppressant in the pharmacological treatment of vestibular or cochleovestibular disorders due to different causes. We reviewed the medical records of 3,357 outpatients treated with a 0.5 or 1.

[Auditory evoked potentials evaluation of the brain stem in multiple sclerosis].

The aim of this study was to evaluate the incidence of auditory and neurotological disorders in multiple sclerosis (MS). Twenty female and 9 male with a definite diagnosis of multiple sclerosis without signs of involvement of the brain stem underwent an audiological and an early auditory evoked potentials (EAEP). The wave forms were classified according to Jerger's (1986) classification.