Depression rates in individuals with type 2 diabetes (T2D) are significantly higher (50%) compared to the general US adult population (18%), alongside increased inflammation markers linked to hyperglycemia.
A case report highlighted a 59-year-old sedentary woman with T2D and depression, who underwent an 8-week structured resistance training program, leading to a 135% increase in strength and a reduction in depressive symptoms.
Despite improvements in strength, fitness, and mental health, the resistance training did not affect key diabetes markers (HbA1c, HOMA-IR, or inflammation), highlighting the importance of integrating exercise into a broader treatment strategy for T2D management.