Publications by authors named "Mario Hernandez-Somerson"
Efficacy and safety of drugs in residual cardiovascular risk: A systematic review of the literature.
Int J Cardiol Cardiovasc Risk Prev
September 2024
Article Synopsis
- The research aims to assess the effectiveness and safety of various drugs in addressing the residual risks associated with atherosclerotic cardiovascular disease, focusing on lipid, inflammatory, and thrombotic components.
- A systematic review of randomized clinical trials was performed, analyzing 18 studies using several databases and assessing biases, with half showing low bias risk.
- Key findings indicated that specific drugs like ethyl eicosapentaenoeic acid and colchicine significantly reduced associated risks without a notable increase in serious adverse events, apart from increased bleeding with some therapies.
Rosuvastatin, is a widely-used statin for the treatment of hypercholesterolemia and the prevention of cardiovascular diseases. Although rosuvastatin is well tolerated, about 3/10.000 patients can suffer severe myopathy.
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