Cancer has overtaken cardiovascular disease as the commonest cause of death in Scottish type 2 diabetes patients: A population-based study (The Ayrshire Diabetes Follow-up Cohort study).

Aims/introduction: The increased mortality risk associated with diabetes is well established. The aim of the present study was to determine the causes of death of people with type 2 diabetes in Ayrshire and Arran, Scotland, between 2009 and 2014, and compare them with the national mortality rates.

Materials And Methods: The primary causes of death were collated.

Improved survival and 30-day mortality after gastrostomy in Scottish motor neurone disease patients: evidence from a national retrospective cohort study using STROBE criteria.

: Defining historical changes and outcomes in the use of gastrostomy in the management of Scottish MND patients. : The 1989-1998 and 2015-2016 Scottish national MND cohorts were used to examine the frequency, timing, and survival related to gastrostomy. The cohorts were censored for survival analysis.

Mortality risk remains higher in individuals with type 1 diabetes: A population-based cohort study (the Ayrshire diabetes follow-up cohort [ADOC]).

Aims: Type 1 diabetes is associated with an increased risk of cardiovascular disease and all-cause mortality. Numerous studies have demonstrated that outcomes for diabetes are improved by intensive glycaemic control, blood pressure control, and treatment of dyslipidaemia in addition to cessation of smoking. The aim of this study was to compare mortalities in individuals with type 1 diabetes with that in non-diabetic individuals, and to investigate the effects of age, gender, glycaemic control, socio-economic status, hypertension, ischaemic heart disease (IHD), smoking status, body mass index (BMI) and dyslipidaemia.

Gout and diabetes: a common combination.

The aims of this cross-sectional study were to compare metabolic parameters in people with gout and diabetes with gout only and type 2 diabetes mellitus (T2DM) only. Fifty General Practices in NHS Ayrshire and Arran (population 340 377) contributed data. The sample was split into three groups, those with both gout and T2DM, those with gout only and those with T2DM only.

Thrice-Weekly Nocturnal In-Centre Haemodiafiltration: A 2-Year Experience.

Background: Adequate control of plasma phosphate without phosphate binders is difficult to achieve on a thrice-weekly haemodialysis schedule. The use of quotidian nocturnal dialysis is effective but not practical in the in-centre setting. This quality improvement project was set up as an exercise allowing the evaluation of small-solute clearance by combining convection with extended-hour dialysis in a thrice-weekly hospital setting.

Socio-economic status influences chronic kidney disease prevalence in primary care: a community-based cross-sectional analysis.

Background: Primary care chronic kidney disease (CKD) registers report widely varying prevalence within the UK. We examined the effects of laboratory ascertainment and adjusting for practice-level variables on the variation in CKD prevalence. We carried out an Ayrshire-wide laboratory database analysis of primary care practices (PCPs).

Statistical approaches to assessing single and multiple outcome measures in dry eye therapy and diagnosis.

Dry eye is a multifactorial disease which would require a broad spectrum of test measures in the monitoring of its treatment and diagnosis. However, studies have typically reported improvements in individual measures with treatment. Alternative approaches involve multiple, combined outcomes being assessed by different statistical analyses.

Investigating the use of simulation as a teaching strategy.

Aim: To compare the performance of two groups of pre-registration nursing students exposed to two different methods of simulation as a teaching strategy, with the aim of providing an evidence base to assist in the selection of appropriate teaching methods, and to inform resource allocation with regard to teaching clinical skills.

Method: A longitudinal, comparative quasi-experimental design, including a validated and piloted assessment tool, was used to evaluate students' performance within three domains: cognitive (knowledge and decision making), motor and affective. Students also completed self-assessments of confidence and anxiety levels.

Comparison of two fixed activities of radioiodine therapy (370 vs. 555 MBq) in patients with Graves' disease.

Objective: Radioiodine therapy is the most commonly used therapy for patients with Graves' disease (GD) in the United Kingdom. It is considered safe, effective and relatively inexpensive. The aim of our study was to examine the outcome of 131Iodine therapy in patients with GD when two different activities of 131Iodine were used.