Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial.

Background: Physicians may use either insulin or exenatide injections for patients with type 2 diabetes mellitus who have poor glycemic control despite taking oral blood glucose-lowering drugs.

Objective: To compare effects of exenatide and insulin glargine on glycemic control in patients with type 2 diabetes mellitus that is suboptimally controlled with metformin and a sulfonylurea.

Design: 26-week multicenter, open-label, randomized, controlled trial.