Publications by authors named "Mario Flores-Torres"

Article Synopsis
  • The study investigated how combinations of specific signs and symptoms can identify individuals in the early stages of Parkinson's disease (PD), analyzing data from over 6,100 men for an average of 3.4 years.
  • Findings revealed that men with constipation, probable REM sleep behavior disorder (pRBD), and hyposmia had a significantly higher risk (23-fold) of developing PD compared to those without these symptoms, and similar high risks were associated with a calculated probability of prodromal PD.
  • The research suggests that these symptom combinations can be effective in predicting future PD and could be used in screening efforts for potential prevention trials.
View Article and Find Full Text PDF

To determine subclinical cardiovascular disease (sCVD) in middle-aged women with clinically manifested hand osteoarthritis (HOA) and to improve the characterization of cardiovascular risk in this population. We cross-sectionally evaluated the relationship between HOA and sCVD in 1,803 volunteers from the Mexican Teachers' Cohort. From 2012 to 2016, a subsample from Mexico City, the Northern state Nuevo León, and the Southern states Chiapas and Yucatán was invited for clinical evaluations, during which neurologists examined carotid arteries using ultrasound, and a standardized HOA questionnaire was also administered.

View Article and Find Full Text PDF

Background: Flavonoids have been proposed to reduce the risk of Parkinson's disease (PD). However, results from epidemiological studies have been inconclusive.

Objective: To prospectively examine the association between the intake of flavonoids and their subclasses and the risk of PD and how pesticides may confound or modify that association.

View Article and Find Full Text PDF

Background: A shared biological component between melanoma and Parkinson's disease (PD) has been suggested. Yet, epidemiological evidence is scarce.

Objective: To examine the association of hair color and family history of melanoma, two strong predictors of melanoma risk, with the occurrence of PD.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates whether subjective cognitive decline (SCD) is more common in women showing early signs of Parkinson's disease (PD) compared to those without these signs.
  • Women with key prodromal PD features, like hyposmia and constipation, reported significantly worse SCD, with odds of poor cognition increasing markedly, especially in younger women under 75.
  • Findings indicate that SCD could be an early indicator of PD, highlighting its relevance in identifying individuals at risk during the initial stages of the disease.
View Article and Find Full Text PDF

Hair cortisol concentration (HCC) represent a potential biomarker of chronic psychological stress. Previous studies exploring the association between perceived stress and HCC have been limited to relatively small and selected populations. We collected hair samples from 881 women from the Mexican Teachers' Cohort (MTC) and 398 women from the Icelandic SAGA pilot-cohort following identical protocols.

View Article and Find Full Text PDF

Background: Folate and vitamins B6 and B12 have been proposed as protective against the development of Parkinson's disease (PD). Two prior longitudinal studies were inconclusive.

Objective: The aim was to examine the association of long-term intake of folate, vitamin B6, and vitamin B12 with the incidence of PD.

View Article and Find Full Text PDF

To determine whether long-term sun exposure has a protective role in subclinical cardiovascular disease in adult Mexican women. We conducted a cross-sectional analysis of a sample of women from the Mexican Teachers' Cohort (MTC) study. Sun exposure was assessed in the MTC 2008 baseline questionnaire, in which women were asked about their sun-related behavior.

View Article and Find Full Text PDF

Objective: To examine the factor structure of the 4- and 10-item Perceived Stress Scale (PSS) among 1 310 Mexican women participating in a prospective cancer cohort study.

Materials And Methods: We performed exploratory and confirmatory factor analyses in two sub-samples of the Mexican Teachers' Cohort. We evaluated internal consistency, estimated the correlation between PSS-4 and PSS-10, and assessed their correlation with a depressive symptoms scale.

View Article and Find Full Text PDF

Purpose: To investigate the association between serious financial difficulties (SFD), stress, and cardiovascular health in women.

Methods: We categorized 1759 employed and insured disease-free women from the Mexican Teachers' Cohort according to their response to a question on SFD included in the Life Stressor Checklist-Revised administered in 2012 and 2016. We also measured perceived stress (n = 1598) and hair cortisol levels (n = 539) in study participants.

View Article and Find Full Text PDF

Women are exposed to a variety of life stressors, particularly violence, during their lifetime which increases the risk of developing various psychiatric and somatic diseases, with the dysregulated secretion of cortisol as one potential biological mechanism. We examined the association between violence and other life stressors and hair cortisol concentration (HCC) in a population of urban women. We included 470 adult women (age = 21-86 years) attending the Cancer Detection Clinic in Iceland.

View Article and Find Full Text PDF

Objective: Subtle cognitive deficits can occur during the prodromal phase of Parkinson's disease (PD), commonly in conjunction with hyposmia. However, little is known about the association between cognitive function and other features suggestive of prodromal PD. We evaluated the association of non-motor prodromal PD features, including hyposmia, constipation and probable REM sleep behaviour disorder (pRBD), with objective measures of cognitive function and self-reported cognitive decline.

View Article and Find Full Text PDF

To describe the prevalence and correlates of depressive symptoms, generalized anxiety disorder (GAD), and perceived negative mental health impact during the SARS-Cov-2 pandemic in Mexico City and evaluate their association with adherence to stay-at-home directives. Baseline data from a cohort study of 2,016 Mexico City government employees were analyzed using multivariable logistic regression models. Among participants, 17.

View Article and Find Full Text PDF

To examine the association between family member incarceration, psychological stress, and subclinical cardiovascular disease (CVD). Between 2012 and 2016, 1849 CVD-free women from the Mexican Teachers' Cohort responded to questions on family incarceration from the Life Stressor Checklist. Perceived stress and hair cortisol levels were measured in a subset of participants.

View Article and Find Full Text PDF

Background: Childhood adversities are prevalent worldwide and might affect adult cardiovascular health. However, in middle-income countries such as Mexico, research on the impact of childhood adversities on cardiovascular disease (CVD) in adulthood is lacking.

Objective: To evaluate the prevalence of adverse childhood experiences (ACEs) and their association with risk factors for CVD in adult Mexican women.

View Article and Find Full Text PDF

Background: Cardiovascular disease in women often develops without conventional risk factors. Prenatal loss is a common pregnancy outcome that may result in physiological changes can increase the potential future risk of cardiovascular disease. Insufficient information exists regarding the impact of pregnancy loss on early markers of cardiovascular disease risk.

View Article and Find Full Text PDF

Background: Violence against women has become a global public health threat. Data on the potential impact of exposure to violence on cardiovascular disease are scarce.

Methods And Results: We evaluated the association between exposure to violence and subclinical cardiovascular disease in 634 disease-free women from the Mexican Teachers' Cohort who responded to violence-related items from the Life Stressor Checklist and underwent measures of carotid artery intima-media thickness in 2012 and 2013.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionpd5meqn421cinjru505h7v398m5f4etd): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once