Progression of serum creatinine and glomerular filtration rate in neonatal critical care patients during the first seven days of life.

Background: Serum creatinine and estimated glomerular filtration rate (GFR) are key indicators of kidney function.

Methods: This descriptive, retrospective study included neonatal patients admitted to a tertiary hospital's neonatal intensive care unit from January 2013 to December 2016. Data on kidney function were collected from birth to 7 days of life.

Association between central corneal thickness and systemic lupus erythematosus: a cross-sectional study protocol.

Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple systems and classified under connective tissue disorders. Ocular involvement occurs in up to 30% of SLE cases, with the cornea being particularly susceptible to thinning due to immune-complex deposits and its predominantly type I collagen composition. This corneal thinning is clinically significant in glaucoma, where patients with reduced central corneal thickness (CCT) may have up to a threefold increased risk of developing glaucoma, as well as in refractive surgery.

Visual and patient reported outcomes provided by a refractive multifocal intraocular lens based on continuous transitional focus.

Purpose: To analyze the quality of vision of patients implanted bilaterally with the multifocal Precizon Presbyopic intraocular lens (IOL), as well as to evaluate the visual performance provided by the lens.

Setting: Vissum Miranza Alicante.

Design: Prospective multicenter study.

Managing dissatisfaction after multifocal intraocular lens implantation through lens exchange using monofocal or alternative multifocal IOLs.

Purpose: To manage patient dissatisfaction following multifocal intraocular lens (MF-IOL) implantation by IOL exchange with either a monofocal or an alternative MF-IOL, and to compare outcomes in these two groups.

Methods: MF-IOL exchange was performed in 32 patients (64 eyes) with neuroadaptation failure. The MF-to-MF group involved patients who had a MF-IOL exchanged with another MF-IOL of a different optical profile and the MF-to-MO group involved patients who had a MF-IOL exchanged to a monofocal IOL.

Clinical Evaluation of a New Spectral-Domain Optical Coherence Tomography-Based Biometer.

The VEMoS-AXL system is a new optical biometer based on spectral domain optical coherence tomography (SD-OCT) that has been tested in terms of intrasession repeatability and compared with a swept-source optical coherence tomography biometer (SS-OCT), which is recognized as the gold standard for the performance of an agreement analysis. A biometric analysis was performed three consecutive times in 120 healthy eyes of 120 patients aged between 18 and 40 years with the SD-OCT system, and afterwards, a single measurement was obtained with the SS-OCT system. Within-subject standard deviations were 0.

Perioperative intense pulsed light to prevent and improve symptoms of post-laser corneal refractive surgery dry eye. A randomized clinical trial.

Purpose: To evaluate the efficacy of perioperative IPL therapy in preventing postoperative ocular surface disorders in patients undergoing corneal laser refractive surgery.

Design: randomized, controlled, clinical trial with triple-blinding.

Methods: Setting: Vissum Miranza - Alicante; Study population: 61 patients randomized in two groups: 31 study patients (perioperative IPL + laser refractive surgery) and 30 control patients (perioperative placebo + laser refractive surgery).

Assessing the role of visual dysfunctions in the association between visual symptomatology and the use of digital devices.

Purpose: To evaluate the association between visual symptoms and use of digital devices considering the presence of visual dysfunctions.

Methods: An optometric examination was conducted in a clinical sample of 346 patients to diagnose any type of visual anomaly. Visual symptoms were collected using the validated SQVD questionnaire.

Comparative Analysis of Strabismus Measurement Using a Video Oculagraphy System and Alternate Prism Cover Test.

Purpose: The aim of the study was to compare distance vision measurements obtained with video oculography (VOG) and an alternate prism cover test (APCT).

Design: Single-center, retrospective, and cross-sectional.

Methods: Eighty-seven subjects with strabismus were included.

Causes of intraocular pseudophakic lens explantation in Spain.

Purpose: To report the causes of pseudophakic intraocular lens (IOL) explantation in Spain over a 20 year period.

Methods: Multicenter observational prospective study of a consecutive series of cases corresponding to pseudophakic intraocular lenses explantations performed in 22 Spanish clinical centres from 2002 to 2021, within a national clinical research network. The clinical data of all IOL explantation patients was evaluated, and the different causes for IOL explantation were systematically analyzed.

Bilensectomy: Safety and Visual Outcomes in Angle-Supported, Iris-Fixated, and Posterior Chamber Phakic Intraocular Lenses.

Purpose: To report the visual and refractive outcomes, intraoperative and postoperative complications, and main causes of bilensectomy in the different types of phakic intraocular lenses (pIOLs).

Methods: This was a retrospective multicenter study that included 234 eyes of 185 patients that underwent bilensectomy. Patients were divided into three groups depending on the pIOL that was explanted (angle-supported, iris-fixated, or posterior chamber).

FS-LASIK for the treatment of moderate-to-high hyperopia.

Purpose: To report modern outcomes of femtosecond laser-assisted cataract surgery (FS-LASIK) for the correction of moderate-to-high hyperopia (≥3.50 diopters [D] and ≤6.50 D), excluding low or very high hyperopia.

Efficacy and safety of intense pulsed light direct eyelid application.

To describe the efficacy and safety of intense pulsed light (IPL) applied directly on the eyelids of patients with Meibomian gland dysfunction (MGD) without corneal shield protector. Observational retrospective single centre study where patients underwent 3 treatment sessions of IPL with 2 weeks of interval. The IPL was carried out with Lumenis OPT M22 with a double pass technique of 12 impacts on the infraorbital/lower eyelid region with the 15 × 35 mm guide light (step 1) and a double pass technique of 3 impacts over the upper eyelids with the 8 × 15 mm guide light (step 2).

Corneal Epithelium Thickness and Refractive Changes After Myopic Laser Corneal Refractive Surgery.

Purpose: To evaluate the postoperative changes in corneal epithelium thickness and refractive power after femtosecond laser-assisted laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) for myopia correction using anterior segment optical coherence tomography (OCT) with an integrated Placido disc topographer.

Methods: The VisuMax 500-kHz femtosecond laser (Carl Zeiss Meditec AG) and Amaris 750 excimer laser (SCHWIND eye-tech-solutions) were used. Central, paracentral, and 6-mm epithelial thickness values were obtained, and the change in the value of epithelial thickness was calculated.

Patients' dissatisfaction with multifocal intraocular lenses managed by exchange with other multifocal lenses of different optical profiles.

Background: The aim of the study was to evaluate the outcomes of dissatisfied patients reporting poor visual quality following implantation of multifocal intraocular lenses (MF-IOLs), managed by IOL exchange with another multifocal optical profile.

Methods: This is a retrospective series of cases. MF-IOL exchange was done in 15 dissatisfied patients (30 eyes) with the perception of poor visual quality for far distance affected by neuroadaptation failure.

Validation of the Symptom Questionnaire for Visual Dysfunctions (SQVD): A Questionnaire to Evaluate Symptoms of any Type of Visual Dysfunctions.

Purpose: To assess psychometric properties of the Symptom Questionnaire for Visual Dysfunctions (SQVD) questionnaire, including accuracy, validity, and reliability, in a clinical sample of patients having any type of visual dysfunction.

Methods: A clinical sample of 306 patients self-administered the SQVD. Rasch analysis was performed to analyze the functionality of the response categories, fit statistics, differential item functioning (DIF), person and item reliability, targeting, local dependency, unidimensionality, and transformation table.

Corneal stromal thickness changes after myopic laser corneal refractive surgery.

Purpose: To evaluate the postoperative behavior of the central corneal stromal thickness after myopic femto-laser-assisted in-situ keratomileusis (LASIK) and small-incision lenticule extraction (SMILE) by using combined anterior segment optical coherence tomography and a Placido disk topographer and to compare the accuracy of both laser machines in predicting the real stromal change.

Setting: Vissum Miranza, Alicante, Spain.

Study Design: Prospective, observational, comparative study.

Rasch analysis for development and reduction of Symptom Questionnaire for Visual Dysfunctions (SQVD).

To develop the Symptom Questionnaire for Visual Dysfunctions (SQVD) and to perform a psychometric analysis using Rasch method to obtain an instrument which allows to detect the presence and frequency of visual symptoms related to any visual dysfunction. A pilot version of 33 items was carried out on a sample of 125 patients from an optometric clinic. Rasch model (using Andrich Rating Scale Model) was applied to investigate the category probability curves and Andrich thresholds, infit and outfit mean square, local dependency using Yen's Q3 statistic, Differential item functioning (DIF) for gender and presbyopia, person and item reliability, unidimensionality, targeting and ordinal to interval conversion table.

Delphi methodology for symptomatology associated with visual dysfunctions.

To analyse what eyecare clinicians think about which symptoms are associated with refractive, accommodative and binocular dysfunctions, and which of them should be used in a questionnaire of visual symptomatology. A Delphi method was developed, using a coordinating group and a group of experts, and the process was conducted in three rounds. In the first round we compiled a list of 34 symptoms from the scientific literature and additional 10 suggested by the experts.

Laser-assisted in situ keratomileusis long term outcomes in late adolescence.

Purpose: Evaluate the long term outcomes of myopic-LASIK in a late adolescent population (age ⩾17 and <20 at the time of surgery).

Methods: Monocentric retrospective case series study. Eyes with at least 3 years of follow-up time were included.

Laser flap enhancement 5 to 9 years and 10 or more years after laser in situ keratomileusis: Safety and efficacy.

Purpose: To study the safety and efficacy of refractive enhancement by flap lifting 5 and 10 years after laser in situ keratomileusis (LASIK).

Setting: Vissum Alicante, Spain.

Design: Retrospective case series.

Measuring the heterophoria: Agreement between two methods in non-presbyopic and presbyopic patients.

Purpose: To establish whether the cover test and von Graefe methods are interchangeable in a non-presbyopic and presbyopic population.

Methods: We performed a prospective study on a sample of 127 non-presbyopic subjects between 20 and 45 years old and 56 presbyopic between 40 and 78 years old. Distance and near vision phoria were measured using the von Graefe method (VG) and cover test (CT).

Accommodative and binocular dysfunctions: prevalence in a randomised sample of university students.

Background: The aim was to analyse the prevalence of symptomatic accommodative and non-strabismic binocular dysfunctions in a randomised population of university subjects.

Methods: A cross-sectional study was conducted with a randomised sample of 175 university students aged between 18 and 35 years. All subjects were given a visual examination in which their symptoms were recorded, as well as performing objective and subjective refractive examinations and accommodative and binocular tests.