Association of the Specimen and Tumor Bed Margin Status with Local Recurrence and Survival in Open Partial Laryngectomy.

: Positive margins are associated with locoregional recurrence in early laryngeal cancer. The aim of this study was to evaluate the impacts of specimen-driven (ex vivo) positive margins on patients with early-stage laryngeal cancer whose tumor bed (defect-driven) margins had been negative. : A retrospective study was performed on 60 consecutive T1b/T2 glottic cancer patients who underwent open frontolateral laryngectomy.

The methodological and reporting quality of randomized controlled trials of tyrosine kinase inhibitors for advanced differentiated thyroid cancer: Meta-research study.

Introduction: Clinical trials on tyrosine kinase inhibitors (TKI) treatment have shown an improvement in overall and progression-free survival in patients with advanced differentiated thyroid cancer. However, it is necessary to evaluate these studies to assess methodological biases and inconsistencies that may impact the effects.

Objective: To map and assess the methodological quality of randomized clinical trials (RCTs) regarding randomization, allocation concealment, blinding, and selective reporting bias.

Medical students' and residents' views on euthanasia.

Background: Doctors are increasingly faced with end-of-life decisions. Little is known about how medical students approach euthanasia. The objective of this study was to evaluate, among medical students and residents, the view on euthanasia and its variants; correlate such a view with empathy and religiosity/spiritualism; and with the stages of medical training in Brazil.

Neck recurrence in papillary thyroid carcinoma.

Introduction: papillary thyroid carcinoma is a tumor with good prognosis. However, some patients treated present neck recurrence.

Objective: to evaluate the risk factors for neck recurrence.

Correction to: Cervicofacial and Pharyngolaryngeal Lymphedema and Deglutition After Head and Neck Cancer Treatment.

The original version of this article unfortunately contained a mistake. Figure 2 was repeated in Figure 3.

Cervicofacial and Pharyngolaryngeal Lymphedema and Deglutition After Head and Neck Cancer Treatment.

One of the sequelae of head and neck cancer treatment is secondary lymphedema, with important impact on breathing, swallowing and vocal functions. The aim of the study was to assess the presence, staging characteristics and relationship of external and internal lymphedema and dysphagia after head and neck cancer treatment. The MDACC Lymphedema Rating Scale in Head and Neck Cancer was employed for the assessment and staging of face and neck lymphedema; the Radiotherapy Edema Scale for internal lymphedema; and a fiberoptic endoscopic evaluation of swallowing (FEES) for swallowing.

Submandibular gland excision.

Objective: to analyze the value of fine needle aspiration and the rates of postoperative complications in patients undergoing resection of the submandibular gland.

Methods: we analyzed the records of patients treated with resection of the gland from January 1995 to December 2008. The data collected included age, gender, findings on clinical history, surgical procedure, results of fine needle aspiration (FNA), pathological diagnosis and complications.

[Pharyngocutaneous fistula following total laryngectomy].

Unlabelled: Pharyngocutaneous fistula (PCF) is the most common complication after total laryngectomy.

Objectives: To establish the incidence of this complication and to analyze the predisposing factors.

Method: This is a cross-sectional study of a historical cohort including 94 patients who underwent total laryngectomy.

Videolaryngostroboscopy and voice evaluation in patients with rheumatoid arthritis.

Unlabelled: Arthritis may affect the larynx and produce symptoms such as hoarseness and vocal fatigue.

Objective: This paper aimed to evaluate the laryngeal manifestations of rheumatoid arthritis.

Methods: This is prospective study assessed 27 patients with rheumatoid arthritis with the aid of videolaryngostroboscopy, auditory-perceptual analysis of the speech using the GIRBAS scale, acoustic analysis and the Voice Handicap Index questionnaire.

[Neck dissection complications].

Because of the proximity of vital structures, certain complications are inherent to neck dissection (ND) for the treatment of patients with squamous cell carcinoma of the upper aerodigestive tract. To establish the incidence of complications of ND. A cross-sectional retrospective study of patient registries.

[Risk factors for distant metastasis in head and neck cancer].

Objective: To identify risk factors for the development of distant metastasis (MD) among patients with head and neck squamous cell carcinoma (SCC) surgically treated.

Methods: A retrospective study of 253 patients from January, 1997 to December, 2002 was performed. Out of them, 10 patients presented DM during the follow up.

[Prognostic factors and comorbidity impact upon the frontolateral laryngectomy].

Objective: To evaluate the survival rates, comorbidity impact, complications, and treatment failure facts.

Methods: 38 patients clinically staged as T1b / T2N0M0 glottic tumors were analyzed. They underwent frontolateral laryngectomy with reconstruction, from January, 1995 to December, 2006.