Angiotensin-Converting Enzyme Related-Polymorphisms on Inflammation, Muscle and Myocardial Damage After a Marathon Race.

Muscle damage is one of the most important factors that affect muscle fatigue during endurance exercise. Recent evidence suggests that the renin-angiotensin system impacts on skeletal muscle wasting. The aim of this study was to determine association between the Met235Thr, I/D and -9/+9 polymorphisms with inflammation, myocardial and muscle injury induced by endurance exercise.

Association Between Hematological Parameters and Iron Metabolism Response After Marathon Race and Genotype.

α-Actinin-3 ( R577X, rs.1815739) polymorphism is a genetic variation that shows the most consistent influence on metabolic pathway and muscle phenotype. XX genotype is associated with higher metabolic efficiency of skeletal muscle; however, the role of polymorphism in oxygen transport and utilization system has not yet been investigated.