Author Correction: Introducing PIONEER: a project to harness big data in prostate cancer research.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Introducing PIONEER: a project to harness big data in prostate cancer research.

Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is to provide high-quality evidence on prostate cancer management by unlocking the potential of big data. The project has identified critical evidence gaps in prostate cancer care, via a detailed prioritization exercise including all key stakeholders.

Physical activity, dipping and haemodynamics.

Objective: To determine the effect of physical activity on diurnal blood pressure (BP) and haemodynamic variation.

Methods: Ambulatory measurements were performed during 24 h in 36 subjects (18 hypertensive, 13 male), aged 49.7 +/- 13.

Reproducibility of intra-arterial ambulatory blood pressure: effects of physical activity and posture.

Objective: To examine the effects of physical activity, body posture and sleep quality on the reproducibility of continuous ambulatory blood pressure monitoring.

Methods: Measurements were performed in 35 subjects (18 hypertensive, 11 male), mean +/- standard deviation age 49 +/- 13 years. Blood pressure (BP) was measured in the brachial artery, and beat-to-beat values of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure and heart rate (HR) were computed.

Haemodynamic responses to physical activity and body posture during everyday life.

Objective: To determine the relationships between body posture and physical activity and systemic haemodynamics during everyday life.

Methods: Continuous measurements were performed in 34 subjects (16 hypertensive, 12 male), aged 49 +/- 13 (mean +/- standard deviation) years. Blood pressure (BP) was measured in the brachial artery.

Determinants of ambulatory blood pressure response to physical activity.

Objectives: Previous studies reported that the association between physical activity, measured with a wrist-worn accelerometer, and ambulatory blood pressure is rather weak and that the inter-individual variation in the degree of association is high. The aim of the present study was to quantify the responses of ambulatory blood pressure (BP) and heart rate (HR) to physical activity, and to determine the effect of age, gender, body mass index, mean BP and HR level and the use of antihypertensive medication on these responses.

Patients And Methods: Twenty-seven subjects (24 hypertensive) underwent 24-h ambulatory monitoring of BP, HR and physical activity.