Introduction: Guided endodontics recently offers a conservative solution for conducting root canal treatment in cases of obliterated canals, but guide mispositioning remains a challenge. Recently, intraoral scanners (IOS) were proposed to detect deviations, but their effectiveness compared to expert visual assessments during guide insertion is uncertain. The objective of the present study was to primarily compare the risk of deviation predicted by an IOS versus expert assessment and secondarily identify factors influencing this risk.
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