Publications by authors named "Marine Helene Laporte"
Article Synopsis
- Cilia assembly in metazoans involves crucial steps such as centriole maturation, migration to the cell surface, and docking with the plasma membrane; mutations affecting these processes are linked to severe ciliopathies.*
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- The study uses Paramecium as a model organism to discover that proteins CEP90, FOPNL, and OFD1 are essential for ciliogenesis and are conserved across different species.*
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- The research reveals that these proteins localize at the distal ends of centrioles/basal bodies and require an additional component, Moonraker (MNR), for proper recruitment and assembly in mammalian cells.*
