Real-life practice of reflectance confocal microscopy in France: A prospective multicenter study.

Background: Studies demonstrating the potential utility of reflectance confocal microscopy (RCM) have been performed under experimental conditions.

Objective: To provide an overview of RCM practice in real-life.

Methods: A multicenter, prospective study carried out in 10 university dermatology departments in France.

Survival and Prognostic Factors in Patients with Aggressive Cutaneous T-cell Lymphomas.

Aggressive primary cutaneous T-cell lymphomas include advanced-stage mycosis fungoides (stage ≥ IIB mycosis fungoides), Sézary syndrome, gamma/delta cutaneous lymphoma, nasal type lymphoma, aggressive epidermotropic CD8+ T-cell lymphoma and some cutaneous lymphomas not otherwise specified. To evaluate their long-term prognosis, we conducted a retrospective cohort study of 85 patients diagnosed between 2005 and 2020 with advanced-stage mycosis fungoides (n = 48), Sézary syndrome (n = 28) or aggressive non-mycosis fungoides/Sézary syndrome subtypes (n = 9). The median survival times in these 3 groups were 118.