Publications by authors named "Marine Camus Duboc"

Background And Study Aims: Lower gastrointestinal bleeding (LGIB) is a common condition linked to increased morbidity, healthcare costs, and mortality. Currently, no prospectively validated prognostic model exists to predict mortality in LGIB patients. Our aim was to develop and validate a risk score that could accurately predict in-hospital mortality of patients admitted for LGIB.

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Background and study aims We aimed to identify risk factors and salvage technique for technical failures of endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) and evaluate the short and long-term consequences in patients with biliary obstruction. Patients and methods This retrospective multicenter study included EUS-CDS from 2018 to 2024. Cases were defined as technical failure and classified as follow: type1 (digestive-flange mispositioned), type2 (biliary-flange mispositioned), type3 (stent deployment failure), type4 (catheter-LAMS through the bile duct), and type5 (others).

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Introduction: This document is a summary of the French intergroup guidelines of the management of biliary tract cancers (BTC) (intrahepatic, perihilar and distal cholangiocarcinomas, and gallbladder carcinomas) published in September 2023, available on the website of the French Society of Gastroenterology (SNFGE) (www.tncd.org).

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Article Synopsis
  • - The study investigated the safety and effectiveness of endoscopic resection for early esophageal tumors in patients with liver cirrhosis or portal hypertension, given their shared risk factors like alcohol use and obesity.
  • - It analyzed data from 112 patients who underwent this procedure between 2005 and 2021, finding that a majority had liver cirrhosis, and various methods were employed to reduce bleeding risks during the surgery.
  • - Results showed high rates of complete and curative resection but also identified some adverse events, such as delayed bleeding and infections; the findings suggest that expert centers should perform these procedures following established guidelines to ensure patient safety and treatment effectiveness.
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1: ESGE recommends that patients with compensated advanced chronic liver disease (ACLD; due to viruses, alcohol, and/or nonobese [BMI < 30 kg/m] nonalcoholic steatohepatitis) and clinically significant portal hypertension (hepatic venous pressure gradient [HVPG] > 10 mmHg and/or liver stiffness by transient elastography > 25 kPa) should receive, if no contraindications, nonselective beta blocker (NSBB) therapy (preferably carvedilol) to prevent the development of variceal bleeding.Strong recommendation, moderate quality evidence. 2: ESGE recommends that in those patients unable to receive NSBB therapy with a screening upper gastrointestinal (GI) endoscopy that demonstrates high risk esophageal varices, endoscopic band ligation (EBL) is the endoscopic prophylactic treatment of choice.

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1: ESGE recommends that the initial assessment of patients presenting with acute lower gastrointestinal bleeding should include: a history of co-morbidities and medications that promote bleeding; hemodynamic parameters; physical examination (including digital rectal examination); and laboratory markers. A risk score can be used to aid, but should not replace, clinician judgment.Strong recommendation, low quality evidence.

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