Publications by authors named "Marinda M Dekker"
Article Synopsis
- Thiosulfate and sulfate are metabolites of hydrogen sulfide, which has cardiovascular protective properties, and their urinary excretion may indicate health outcomes.
- In a study of 6,839 participants, the researchers found that while urinary thiosulfate excretion did not correlate with cardiovascular events, higher sulfate excretion was linked to lower all-cause mortality risk.
- The results suggest that sulfate excretion could be a significant factor in assessing overall health and mortality risk, particularly in individuals with normal lipid levels.
Oxidative stress is a key element of the pathophysiology of heart failure (HF). As free thiols are readily oxidized by reactive oxygen and sulfur species, their circulating level may directly reflect the systemic redox status. This study addresses the role of serum free thiols in chronic HF, which is of particular interest as free thiols are amenable to therapeutic modulation and thus are a potential target for therapy.
View Article and Find Full Text PDF