Prenatal chromosomal microarray analysis: a survey of prenatal genetic counselors' experiences and attitudes.

Objective: Studies showing the efficacy and accuracy of chromosomal microarray analysis (CMA) in prenatal diagnosis may position it as a first-tier prenatal test. This study seeks to characterize the practices and attitudes of North American prenatal genetic counselors regarding CMA.

Method: Genetic counselors (N = 196) in Canada and the USA responded to an anonymous online survey.

Effect of maternal cystic fibrosis genotype on diabetes in pregnancy.

Objective: To evaluate the association between the cystic fibrosis (CF) genotype and the rate of diabetes complicating pregnancy.

Methods: We conducted a retrospective cohort analysis of all pregnant patients with CF from 1972-2011 at a single institution. Patients who were homozygous for the ΔF508 mutation were compared with patients who were heterozygous for the ΔF508 mutation.

22q11.2 deletion syndrome: attitudes towards disclosing the risk of psychiatric illness.

22q11.2 Deletion Syndrome (22q11.2DS) is a common microdeletion syndrome with multisystem features.