Individual titanium and calcium-magnesium phosphates are widely known as effective sorbents. The sorption processes on these phosphates are based on different mechanisms. The sorption efficiency towards different cations depends on the phase composition of the sorbent.
View Article and Find Full Text PDFLithium compounds are of high interest to many industries. The presence of undesirable impurities in Li precursors leads to uncontrolled change in the functional properties of final compounds. Therefore, the development of reliable methods for lithium salt purification is considered a key factor for their application in various industries.
View Article and Find Full Text PDFIn this paper, a universal technology is proposed for processing low-titanium mineral raw material-apatite-nepheline ore waste, including its treatment with sulfuric or hydrochloric acid in a two-stage mode with a sequential increase in the concentration. This technique allowed us to remove nepheline and apatite in the first stage and achieve a titanium mineral content of TiO of more than 30%; in the second stage, we were able to convert the titanium into its precursors-titanyl sulfate monohydrate TiOSO·HO and a hybrid rutile-silica composition. The key stage in the sorbent synthesis is the reaction of the precursor with a phosphoric acid solution.
View Article and Find Full Text PDFBackground: In Germany pancreas transplants are performed in only a few selected and specialized centres, usually combined with a kidney transplant. Knowlegde of the indications for and techniques of transplantation as well as of the histopathological assessment for rejection in pancreas and duodenal biopsies is not very widespread.
Aim: To give an overview of the development and status quo in pancreas-kidney-transplantation in Germany summarizing the experience of the largest German pancreas transplant centre and to give a résumé of the results of histological diagnoses of biopsy specimens submitted between 06/2017 and 12/2020.
In patients with compromised immune function, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (CoVID-19) impose particular challenges. Especially in hematological malignancies, including lymphoma, the demands by this novel virus disease are further enhanced during sophisticated treatments, such as chimeric antigen receptor (CAR) T-cell therapy. Here, we present the first case of a patient with refractory diffuse-large B-cell lymphoma, who underwent CAR T-cell treatment in the context of SARS-CoV-2.
View Article and Find Full Text PDFAn original method based on the use of technogenic waste from the processing of mineral-layered materials, in particular phlogopite for obtaining highly efficient functional compositions of the "mica-TiO", has been developed. The composition core is a nanosized mica flake coated with mesoporous titanium dioxide of an anatase or rutile structure. Energy-saving and environmentally friendly technological methods are based on the splitting of the mica followed by heterogeneous electrohydrolysis of a mixture of titanium (IV) sulfate solution and flake particles.
View Article and Find Full Text PDFTherapeutic strategies for patients with locally advanced rectal cancer (LARC) who are achieving a pathological complete response (pCR) after neoadjuvant radio-chemotherapy (neoCRT) are being increasingly investigated. Recent trials challenge the current standard therapy of total mesorectal excision (TME). For some patients, the treatment strategy of "watch-and-wait" seems a preferable procedure.
View Article and Find Full Text PDFTreatment options for patients with metastatic colorectal cancer (mCRC) are limited. This particularly affects the largest group of patients with RAS mutations, who are considered ineligible for therapy with antiEGFR antibodies. In this liquid biopsy-based study, we performed the first in-depth analysis of the RAS mutational status in initially RAS-mutated patients during first-line therapy.
View Article and Find Full Text PDFThe waste of apatite-nepheline ore processing was chosen as the material of study for the present investigation. The chemical and phase compositions have been analyzed and the route of the new technology has been developed. Treatment of the waste with diluted hydrochloric acid enables to separate apatite, nepheline, titano-magnetite minerals from titanite (CaSiTiO).
View Article and Find Full Text PDFThe treatment of heavy metal-contaminated wastewater is an important action to reduce The negative impacts of industrial wastes on water bodies. This work focuses on The application of a low-cost titanium (IV) phosphate sorbent of TiO(OH)HPO42HO chemical composition toward lead and zinc ions depending on their concentration and The temperature of The solution. The kinetic studies showed that The values of The rate of intraparticle diffusion and The effective diffusion coefficients for Zn were considerably higher than those for Pb.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
February 2020
This work focuses on the synthesis procedure of a new sorbent based on a TiCaMg phosphate. The synthesis strategy includes stepwise interaction between solid precursors and phosphorus-containing agents. The solid precursors were ammonium titanyl sulfate and calcined dolomite, which were used as titanium, calcium, and magnesium sources.
View Article and Find Full Text PDFPurpose: Despite therapeutic improvements, all patients with nonresectable metastatic colorectal cancer (mCRC) acquire resistance to treatment probably due to the growth of mutated clones. In contrast to tissue-based studies, liquid biopsies have enabled the opportunity to reveal emerging resistance to treatment by detecting mutated clones and noninvasively monitoring clonal dynamics during therapy.
Methods: The courses of three patients with mCRC who were initially RAS wild-type were monitored longitudinally using liquid biopsy with long-term follow-up of up to 20 sequential samples.
Amorphous titanium hydroxyphosphate with formula Ti(OH)(1.36)(HPO(4))(1.32).
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