Conjunctival Lymphoma--An International Multicenter Retrospective Study.

Importance: To date, the clinical features of the various subtypes of conjunctival lymphoma (CL) have not been previously evaluated in a large cohort.

Objective: To characterize subtype-specific clinical features of CL and their effect on patient outcome.

Design, Setting, And Participants: A retrospective multicenter study was performed.

Malignant lymphoma of the conjunctiva.

Conjunctival lymphomas constitute 25% of all ocular adnexal lymphomas. The majority are B-cell non-Hodgkin lymphomas (NHLs) (98%), whereas conjunctival T-cell NHLs are rare (2%). The most frequent subtype of conjunctival B-cell lymphoma is extranodal marginal zone lymphoma (EMZL; 81%), followed by follicular lymphoma (8%), diffuse large B-cell lymphoma (3%), and mantle cell lymphoma (3%).