Publications by authors named "Marina Loid"

Article Synopsis
  • The study looks at how the endometrium (the inner lining of the uterus) changes as women get older and whether these changes affect their ability to have babies.
  • It was found that older women (over 45) have different endometrial cells and gene activity compared to younger women, which could make it harder for embryos to implant.
  • The research included 44 women undergoing hormone treatment and examined biopsies to see how ready their endometrium was for pregnancy at different ages.
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Article Synopsis
  • Modern lifestyles are causing women to have babies later, which can lead to problems with getting pregnant as they age.
  • Older age can affect the quality of eggs and the lining of the uterus (endometrium), which are important for pregnancy.
  • There's not a lot of research on how the aging uterus affects getting pregnant, and this review aims to gather information to help improve understanding and treatment options.
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Hyperandrogenic women with PCOS show disrupted decidualization (DE) and placentation. Dihydrotestosterone (DHT) is reported to enhance DE in non-PCOS endometrial stromal cells (eSC); however, this has not been assessed in PCOS cells (eSC). Therefore, we studied the transcriptome profile of non-decidualized (non-DE) and DE eSCs from women with PCOS and Ctrl in response to short-term estradiol (E2) and/or progesterone (P4) exposure with/without (±) DHT.

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