Publications by authors named "Marina Laganaro"

Purpose: The production of speech-like sequences composed of varying syllables has been reported to achieve higher syllable rates than the production of repeated syllables (commonly designed as sequential motion rate [SMR] and alternating motion rate [AMR] tasks, respectively). The faster rate for SMR relative to AMR sequences is explained by different interpretative hypotheses, which remain empirically unexplored. In the present study, we aimed to investigate whether the high syllable rates of SMR sequences are due to the specific sequences used in most studies that involve front-to-back articulatory movements.

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Learning words in the mother tongue is a fundamental lifelong skill that involves complex cognitive and neural changes. In adults, newly learned words affect the organization of the lexical-semantic network and, compared to words that have been in the lexicon for longer, they activate the same cortical areas, but more extensively and/or intensively. It is however still unclear (1) which brain and cognitive processes underlying word production change when infrequent/unknown words are compared before and after learning and (2) whether integrating newly learned words impacts word specific processes or has a broader impact on unlearned words.

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Neurobehavioral studies have provided evidence for the effectiveness of anodal tDCS on language production, by stimulation of the left Inferior Frontal Gyrus (IFG) or of left Temporo-Parietal Junction (TPJ). However, tDCS is currently not used in clinical practice outside of trials, because behavioral effects have been inconsistent and underlying neural effects unclear. Here, we propose to elucidate the neural correlates of verb and noun learning and to determine if they can be modulated with anodal high-definition (HD) tDCS stimulation.

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Behavioral and brain-related changes in word production have been claimed to predominantly occur after 70 years of age. Most studies investigating age-related changes in adulthood only compared young to older adults, failing to determine whether neural processes underlying word production change at an earlier age than observed in behavior. This study aims to fill this gap by investigating whether changes in neurophysiological processes underlying word production are aligned with behavioral changes.

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Introduction: The ability to speak is grounded in general memory and control processes and likely changes across the lifespan. However, our knowledge on how word production abilities naturally evolve from childhood to old age remains marginally investigated. Our aim was to shed further light on this issue by exploiting the contrast between two ways to elicit word production: referential picture naming and inferential naming from definition.

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Speaking involves the preparation of the linguistic content of an utterance and of the motor programs leading to articulation. The temporal dynamics of linguistic versus motor-speech (phonetic) encoding is highly debated: phonetic encoding has been associated either to the last quarter of an utterance preparation time (∼150ms before articulation), or to virtually the entire planning time, simultaneously with linguistic encoding. We (i) review the evidence on the time-course of motor-speech encoding based on EEG/MEG event-related (ERP) studies and (ii) strive to replicate the early effects of phonological-phonetic factors in referential word production by reanalysing a large EEG/ERP dataset.

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Oral diadochokinetic (DDK) tasks are common research and clinical tools used to test oromotor skills across different age groups. They include alternating motion rate (AMR) and sequential motion rate (SMR) tasks. AMR tasks involve repeating a single syllable, whereas SMR tasks involve repeating varying syllables.

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The processes involved in the Stroop task/effect are thought to involve conflict detection and resolution stages. Little is known about the evolution of these two components over the lifespan. It is well admitted that children and older adults tend to show longer response latencies than young adults.

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In certain circumstances, speech and language therapy is proposed in telepractice as a practical alternative to in-person services. However, little is known about the minimum quality requirements of recordings in the teleassessment of motor speech disorders (MSD) utilizing validated tools. The aim here is to examine the comparability of offline analyses based on speech samples acquired from three sources: (1) in-person recordings with high quality material, serving as the baseline/gold standard; (2) in-person recordings with standard equipment; (3) online recordings from videoconferencing.

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For the clinical assessment of motor speech disorders (MSDs) in French, the MonPaGe-2.0.s protocol has been shown to be sensitive enough to diagnose mild MSD based on a combination of acoustic and perceptive scores.

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Purpose: While the involvement of attention in utterance planning is well established at the conceptual and lexical levels, the attentional demands of postlexical processes are still debated. This study investigates the involvement of attentional resources on motor speech encoding during utterance production in the context of Parkinson's disease (PD), a population allowing to assess if the attentional demands observed in a dual-task paradigm (the dual-task costs [DTCs]) are explained by postlexical difficulties and not solely by executive impairment.

Method: Speech production was analyzed in a dual-task paradigm with 30 participants presenting with motor speech disorders due to hypokinetic dysarthria in the context of PD.

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Changes in word production occur across the lifespan, with adolescence representing a knot point between children's and adults' performance and underlying brain processes. Previous studies on referential word production using picture naming tasks have shown a completely adult-like pattern in 17-year-old adolescents and an intermediate pattern between children and adults in adolescents aged 14-16 years old, suggesting a possible involvement of visuo-conceptual processes in the transition from childhood to adulthood. Given the visual nature of the picture naming task, it is unclear whether changes in visuo-conceptual processes are specifically related to the referential word production or if overall changes in conceptual to lexical processes drive maturation.

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Purpose: The clinical diagnosis of motor speech disorders (MSDs) is mainly based on perceptual approaches. However, studies on perceptual classification of MSDs often indicate low classification accuracy. The aim of this study was to determine in a forced-choice dichotomous decision-making task (a) how accuracy of speech-language pathologists (SLPs) in perceptually classifying apraxia of speech (AoS) and dysarthria is impacted by speech task, severity of MSD, and listener's expertise and (b) which perceptual features they use to classify.

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Background: Vocoid epenthesis within consonant clusters has been claimed to contribute to the diagnosis of apraxia of speech. In clinical practice, the clinicians often doubt about the correct production of clusters as the C-C transition may be minimally disrupted.

Aims: To demonstrate the value of acoustic analysis in clinical practice as a reliable complement to perceptive judgment.

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Background: Stroke rehabilitation interventions are routinely personalized to address individuals' needs, goals, and challenges based on evidence from aggregated randomized controlled trials (RCT) data and meta-syntheses. Individual participant data (IPD) meta-analyses may better inform the development of precision rehabilitation approaches, quantifying treatment responses while adjusting for confounders and reducing ecological bias.

Aim: We explored associations between speech and language therapy (SLT) interventions frequency (days/week), intensity (h/week), and dosage (total SLT-hours) and language outcomes for different age, sex, aphasia severity, and chronicity subgroups by undertaking prespecified subgroup network meta-analyses of the RELEASE database.

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Introduction: Impairments in speech and executive functions are both observed in Parkinson's disease (PD) and might be influenced by subthalamic nucleus deep brain stimulation (STN-DBS). We investigated the effects of STN-DBS on speech and executive functions and their mutual interference in PD.

Methods: 14 PD patients eligible for bilateral STN-DBS (PD-DBS), and 16 PD patients with best medical treatment (PD-BMT) were included.

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Even if both phonological and semantic cues can facilitate word retrieval in aphasia, it remains unclear if their respective effectiveness varies according to the underlying anomic profile. The aim of the present facilitation study is to compare the effect of phonological and semantic cues on picture naming accuracy and speed in different types of anomia. In the present within-subject design study, 15 aphasic persons following brain damage underwent picture naming paradigms with semantic cues (categorically- or associatively related) and phonological cues (initial phoneme presented auditorily, visually or both).

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There is a general agreement that speaking requires attention at least for conceptual and lexical processes of utterance production. However, conflicting results have been obtained with dual-task paradigms using either repetition tasks or more generally tasks involving limited loading of lexical selection. This study aimed to investigate whether post-lexical processes recruit attentional resources.

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Numerous studies report that poor readers display low performance in naming tasks. However, very few studies have investigated the development of naming skills along with the development of reading fluency and its variability in typically developing children. In this study, we used electro-encephalographic (EEG) recordings acquired during letter and picture naming tasks to investigate how naming skills develop and, possibly, interact with age and reading level variations.

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To respond to the need of objective screening tools for motor speech disorders (MSD), we present the screening version of a speech assessment protocol (, which is based on semi-automated acoustic and perceptual measures on several speech dimensions in French. We validate the screening tool by testing its sensitivity and specificity and comparing its outcome with external standard assessment tools. The data from 80 patients diagnosed with different types of mild to moderate MSD and 62 healthy test controls were assessed against the normative data obtained on 404 neurotypical speakers, with computed on seven speech dimensions (voice, speech rate, articulation, prosody, pneumophonatory control, diadochokinetic rate, intelligibility) based on acoustic and perceptual measures.

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The lexical-semantic organization of the mental lexicon is bound to change across the lifespan. Nevertheless, the effects of lexical-semantic factors on word processing are usually based on studies enrolling young adult cohorts. The current study aims to investigate to what extent age-specific semantic organization predicts performance in referential word production over the lifespan, from school-age children to older adults.

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The use of electroencephalography (EEG) to study overt speech production has increased substantially in the past 15 years and the alignment of evoked potential (ERPs) on the response onset has become an extremely useful method to target "latest" stages of speech production. Yet, response-locked ERPs raise a methodological issue: on which event should the point of alignment be placed? Response-locked ERPs are usually aligned to the vocal (acoustic) onset, although it is well known that articulatory movements may start up to a hundred milliseconds prior to the acoustic onset and that this "articulatory onset to acoustic onset interval" (AAI) depends on the phoneme properties. Given the previously reported difficulties to measure the AAI, the purpose of this study was to determine if the AAI could be reliably detected with EEG-microstates.

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Changes in word production occur across the lifespan. Previous studies have shown electrophysiological, temporal, and functional differences between children and adults accompanying behavioral changes in picture-naming tasks (Laganaro, Tzieropoulos, Fraunfelder, & Zesiger, 2015). Thus, a shift toward adult-like processes in referential word production occurs somewhere between the ages of 13 and 20.

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Background: Speech and language therapy (SLT) benefits people with aphasia following stroke. Group level summary statistics from randomised controlled trials hinder exploration of highly complex SLT interventions and a clinically relevant heterogeneous population. Creating a database of individual participant data (IPD) for people with aphasia aims to allow exploration of individual and therapy-related predictors of recovery and prognosis.

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