Phytomodulatory proteins isolated from Calotropis procera latex promote glycemic control by improving hepatic mitochondrial function in HepG2 cells.

The medicinal uses of Calotropis procera are diverse, yet some of them are based on effects that still lack scientific support. Control of diabetes is one of them. Recently, latex proteins from latex (LP) have been shown to promote glycemic control by the inhibition of hepatic glucose production via AMP-activated protein kinase (AMPK).