Publications by authors named "Marina Demetriou"
Article Synopsis
- The gut-microbiota-brain axis is a communication system between the gastrointestinal tract and the brain, influencing psychological health.
- Gut dysbiosis, or imbalances in gut bacteria, has been linked to the development of psychosis, especially in relation to early-life stress and various life stressors.
- This review highlights the differences in gut microbiome composition between individuals with first-episode psychosis (FEP) and healthy controls, exploring how these changes may affect symptoms of FEP.
The ongoing coronavirus disease 2019 (COVID-19) pandemic has had a widespread impact on individuals' mental health through indirect psychological and social mechanisms, related to factors such as fear of infection or death, social isolation, lack of social support and financial instability. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has also been associated with the development or recurrence of neuropsychiatric symptoms, both during the acute phase, as well as during the post-acute 'long-COVID' phase. In addition to the COVID-19 survivors with a mental health history that are at a high risk of experiencing a range of neuropsychiatric symptoms following resolution of acute COVID-19, there is accumulating evidence that a diagnosis of COVID-19 may also be associated with new-onset neuropsychiatric morbidity among survivors without pre-existing mental health disorders.
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- Evidence shows that many patients recovering from COVID-19 may continue to experience neuropsychiatric symptoms, such as depression, anxiety, and cognitive deficits, even after their acute illness resolves.
- Factors like COVID-19 severity, sex, pre-existing mental health conditions, and high inflammatory markers increase the risk for these long-lasting symptoms, but more research is needed to connect the dots.
- It's important for healthcare teams to work together to identify patients at risk for persistent neuropsychiatric issues so they can receive proper support and reduce the chances of long-term disability.