Publications by authors named "Marina Delli Colli"
Background: Previous guidelines recommend prompt epinephrine administration, followed by observation in the emergency department (ED). The need for transfer in all cases of anaphylaxis has recently been challenged.
Objective: To evaluate the need for additional ED treatment among children with anaphylaxis who received prehospital epinephrine.
Milk-induced anaphylaxis among children presenting to Canadian emergency departments.
Ann Allergy Asthma Immunol
April 2024
Background: Cow's milk is one of the most common and burdensome allergens in pediatrics, and it can induce severe anaphylactic reactions in children. However, data on cow's milk-induced anaphylaxis are sparse.
Objective: To describe the epidemiology of pediatric cow's milk-induced anaphylaxis and to determine risk factors for repeat emergency department (ED) epinephrine administration.
Article Synopsis
- Epinephrine is really important for treating severe allergic reactions called anaphylaxis, but many people are using other medicines like antihistamines and steroids instead.
- A study looked at how these different treatments worked by collecting information from thousands of patients with anaphylaxis in Canada and Israel.
- The results showed that using epinephrine before getting to the hospital helped reduce serious problems during the allergic reaction, while antihistamines also seemed to help, but steroids made patients need more fluids when they arrived at the emergency room.
Background: Prompt epinephrine autoinjector (EAI) use is the primary treatment for anaphylaxis. However, limited Canadian data exist on the impact of reaction location on EAI use for food-induced anaphylaxis (FIA).
Objective: We sought to investigate the setting, management, and severity of pediatric FIA.
Glucagonomas are rare pancreatic neuroendocrine tumors (pNETs), malignant in 80% of cases, thus highlighting the importance of early diagnosis and treatment. Primary manifestations are diabetes, dermatosis, depression, weight loss, and deep vein thrombosis. Unlike other pNETs, glucagonomas are associated with a higher incidence of thromboembolic events, often resulting in death.
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