Publications by authors named "Marina Calvo-Salvador"
Ceft-to-Ceft Study: Real-Life Experience with Ceftaroline and Ceftobiprole in Treatment of the Principal Infectious Syndromes in a Spanish Multicenter Hospital Cohort.
Antibiotics (Basel)
December 2023
Article Synopsis
- A study compared the effectiveness and safety of ceftaroline fosamil (ceftaroline-F) and ceftobiprole medocaril (ceftobiprole-M) for treating infections in hospitalized patients in Spain.
- Ceftaroline-F was found to be given to younger patients and associated with higher rates of severe infections like bacteremia and infective endocarditis, while ceftobiprole-M was more often used for polymicrobial and Gram-negative infections.
- Both antibiotics had similar infection-related mortality rates and dropout rates due to side effects, but patients on ceftaroline-F had longer hospital stays.
Article Synopsis
- The study investigates the safety and effectiveness of sotrovimab for treating severe COVID-19 in immunocompromised patients, specifically looking at data from October to December 2021.
- Out of 32 patients studied, most were either organ transplant recipients or had blood cancers, with some experiencing respiratory issues and a small percentage dying or needing ventilation.
- Results suggest that early treatment within the first two weeks may lead to better outcomes, and no adverse effects were reported from sotrovimab, indicating it could be a safe option that requires further research.
Article Synopsis
- The study focused on COVID-19-associated pulmonary aspergillosis (CAPA) in critically ill patients, aiming to develop a clinical score to identify those at high risk for CAPA upon ICU admission.
- Factors like age, smoking, existing health conditions, corticosteroid use, and certain therapies were linked to an increased risk of CAPA, leading to the creation of a predictive score that demonstrated high accuracy.
- The proposed CAPA score could help in prioritizing preventive strategies for at-risk patients, though further research is needed to confirm its effectiveness and the benefits of targeted interventions.
Cytomegalovirus (CMV) infection is a well-known factor associated with invasive aspergillosis in immunocompromised hosts. However, its association with COVID-19-associated pulmonary aspergillosis (CAPA) has not been described. We aimed to examine the possible link between CMV replication and CAPA occurrence.
View Article and Find Full Text PDFIncidence, Clinical Presentation, Relapses and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Patients Treated With Anti-CD20 Monoclonal Antibodies.
Clin Infect Dis
May 2022
Background: Our objective is to describe the presentation and complications, including relapses, of coronavirus disease 2019 (COVID-19) in patients under anti-CD20 treatments. In addition, to describe viral clearance and determine the safety of reintroducing anti-CD20 treatment.
Methods: Retrospective cohort study of 422 patients under anti-CD20 treatment that was administered from 1 January 2019 to 31 December 2020.