HutW from Is an Anaerobic Heme-Degrading Enzyme with Unique Functional Properties.

Increasing antibiotic resistance, and a growing recognition of the importance of the human microbiome, demand that new therapeutic targets be identified. Characterization of metabolic pathways that are unique to enteric pathogens represents a promising approach. Iron is often the rate-limiting factor for growth, and , the causative agent of cholera, has been shown to contain numerous genes that function in the acquisition of iron from the environment.