Publications by authors named "Marina A Akimenko"
Article Synopsis
- Current assessment methods for penile cavernous fibrosis in animal models are limited, prompting the study to evaluate micro-computed tomography (micro-CT) as a more effective alternative.
- The study used 25 male rabbits with induced testosterone deficiency, assessing changes in penile samples over a period of 84 days through various analysis methods, including 3D modeling and tissue morphometry.
- Results indicated that micro-CT provided detailed visualization and changes in tissue density, with significant alterations in smooth muscle/connective tissue and collagen ratios observed at different time points, suggesting a relationship between gray value changes and tissue reorganization in fibrosis.
The phenomenon of unstable expression of gap junction's proteins connexins remains a "visiting card" of astrocytic tumors with various degrees of malignancy. At the same time, it stays unclear what is detected by the positive expression of connexins in astrocytic tumors: gap junctions, hemi-channels, or connexin proteins in cytosol. In the present work, for the first time, we demonstrate an ultrastructural evidence of gap junctions in pleomorphic xanthoastrocytoma, a rare primary brain tumor, the intercellular characteristics of which are poorly studied and remain very discursive and controversial.
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