Publications by authors named "Marilza de Moura Ribeiro Carvalho"
Article Synopsis
- - Brazil’s gas stations operate with attendants filling fuel, exposing them to harmful substances known as BTEX, which can lead to serious health issues, including bone marrow degeneration and weakened immune systems.
- - This systematic review analyzed 1,086 articles on biomonitoring gas station workers, identifying 13 key studies that showcase advanced monitoring technologies like immunophenotyping and molecular cytogenetics, along with a focus on the health impacts of benzene exposure.
- - The review concludes that gas station workers are at risk and need ongoing health monitoring due to potential early signs of benzene-related toxicity, but there is no established standard for measuring health indicators effectively.
Long-Term Outcomes of Childhood Acute Lymphocytic Leukemia Treated with Adapted Berlin-Frankfurt-Münster (BFM) Protocols: A Multicentric Analysis from a Developing Country.
Cancers (Basel)
August 2024
Introduction: The objective of the current study was to determine the survival probabilities of children and adolescents with acute lymphocytic leukemia treated with adapted Berlin-Frankfurt-Münster (BFM) protocols and compare our results with the original BFM reports.
Methods: This retrospective study included 695 patients up to 19 years old treated with adapted BFM protocols between 1997 and 2018 in four hospitals in Rio de Janeiro. The 1997-2007 and 2008-2018 cohorts were analyzed separately.
Correction to: The association of three DNA repair genes polymorphisms on the frequency of chromosomal alterations detected by fluorescence in situ hybridization.
Int Arch Occup Environ Health
October 2021
The association of three DNA repair genes polymorphisms on the frequency of chromosomal alterations detected by fluorescence in situ hybridization.
Int Arch Occup Environ Health
October 2021
Article Synopsis
- Gas station workers (GSWs) are exposed to cancer-causing agents, and a study was conducted to link high rates of chromosome alterations in their blood to specific gene variations related to DNA repair.
- The study involved 114 GSWs and compared them with 115 control participants, utilizing cytogenetic analysis and genetic testing for specific gene polymorphisms.
- Results showed that GSWs had significantly higher chromosome alteration rates and more variant alleles in the RAD51 gene, suggesting a connection between this genetic variation and increased genomic instability, which could have implications for cancer prevention in this workforce.
Complex karyotype including ring chromosome 11 in a patient with acute myeloid leukemia: case report.
Sao Paulo Med J
December 2018
Context: Complex karyotypes in acute myeloid leukemia (AML) are characterized by an overall low response rate with frequent relapses after clinical treatment.
Case Report: Here, we describe the case of a 61-year-old obese female with clinically diagnosed AML who presented a complex karyotype involving an uncommon abnormality: ring chromosome 11. Immunophenotypic analysis confirmed the diagnosis.
Background: Central nervous system involvement is considered a rare complication of chronic lymphocytic leukemia, and so there is the risk of being overlooked.
Case Presentation: We report a case of central nervous system involvement in a 75-year-old mulatto woman with chronic lymphocytic leukemia after 5 years of follow-up and a literature review on the subject. The clinical course, treatment and outcome are described.
Introduction: Leptospirosis is a zoonotic disease found in tropical and temperate countries, and its clinical diagnostic confusion with arboviruses (dengue fever, oropouche fever and yellow fever), Brazilian spotted fever, viral hepatitis and hantaviruses has been an ongoing public health concern. The aim of this observational study was to demonstrate an association between findings of atypical lymphocytosis and the progression of endemic leptospirosis.
Methods: A retrospective analysis was performed on the demographic, epidemiological, clinical and laboratory aspects of 27 human leptospirosis cases that occurred over a period of 13 years (1996-2009) with no reported epidemic outbreaks in Rio de Janeiro, Brazil.