Publications by authors named "Marilyn Santacruz"
Front Mol Neurosci
June 2023
Article Synopsis
- Classic experiments showed that peripheral sympathetic neurons rely on NGF for survival, but it's unclear how they become resistant to lacking trophic factors.
- The study investigates how neurons can survive without these factors and identifies key mechanisms, including increased expression of the NGF receptor in sympathetic neurons and the glucocorticoid receptor in hippocampal neurons.
- Understanding these resistance mechanisms has implications for neuropsychiatric conditions, longevity, and neurodegeneration prevention.
