The RHCE allele ceCF: the molecular basis of Crawford (RH43).

Background: The Crawford antigen (RH43) was described in 1980. It occurred in African American people, as a low-prevalence Rhesus antigen, who were also VS+.

Study Design And Methods: Twelve blood samples were analyzed because of inquiries into discrepant reactions in routine anti-D typing.

SCER and SCAN: two novel high-prevalence antigens in the Scianna blood group system.

Background: More than 20 years ago, two probands were described whose red blood cells (RBCs) typed Sc:1,-2,3. Their serum samples contained alloantibodies reactive with all RBCs tested except those of the Sc:-1,-2,-3 phenotype. Cloning of the Scianna gene allowed us to determine the molecular bases of these samples.