Publications by authors named "Marilia Farias de Melo"
Article Synopsis
- * Researchers analyzed the blood of 27 CHIKV-positive patients and 9 healthy controls, finding significant increases in transcription factors and cytokines linked to various T cell types, especially RORγt.
- * The study revealed complex immune interactions during CHIKV infection, noting that higher levels of some immune markers are associated with either lower or higher viral loads, enhancing understanding of disease mechanisms.
Epidemiologic and clinical investigations during a chikungunya outbreak in Rio Grande do Norte State, Brazil.
Joelma D Monteiro Joanna Gardel Valverde Ingryd Camara Morais Cassio Ricardo de Medeiros Souza João Ciro Fagundes Neto Marília Farias de Melo Márcia Cristina Bernardo de Melo Moura
PLoS One
January 2021
The first autochthonous case of chikungunya virus (CHIKV) infection in Brazil was in September 2014 in the State of Amapá, and from there it rapidly spread across the country. The present study was conducted in 2016 in the state of Rio Grande do Norte, and the aims were to describe the epidemiological and the clinical aspects of the CHIKV outbreak. Biological samples from 284 chikungunya suspected cases were screened for CHIKV and Flavivirus (FV) RNA using qRT-PCR.
View Article and Find Full Text PDF