Continuous haemofiltration in acute renal failure with prostacyclin as the sole anti-haemostatic agent.

Objective: To investigate the safety and efficacy of a synthetic prostacyclin analogue (epoprostenol) for circuit maintenance during continuous veno-venous haemofiltration (CVVH) in patients with acute renal failure (ARF).

Design: Observational case study.

Setting: University-affiliated six-bed intermediate renal care unit in a nephrology and internal medicine department of a 1300-bed teaching hospital.