Publications by authors named "Mariko Serizawa"

Article Synopsis
  • * A study involved 212 women who experienced significant blood loss during delivery, revealing a notably higher occurrence of low fibrinogen levels and higher scores on previous criteria in the DIC group compared to controls.
  • * The results demonstrated that the new criteria are effective, reliable, and valid for diagnosing obstetrical DIC, as shown by strong statistical correlations with the previous diagnostic criteria.
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Background:  We previously conducted a primary survey of pregnant women with hereditary thrombophilia based on national surveillance in Japan, but did not examine their thrombosis-related characteristics. Antithrombin (AT) deficiency, protein C (PC) deficiency and protein S (PS) deficiency are the major types of hereditary thrombophilia in Japan.

Methods: We examined their detailed information related to thrombosis, and evaluated peripartum outcomes in comparison with control data obtained from the Japan Society of Obstetrics and Gynecology.

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Article Synopsis
  • Japanese guidelines recommend blood transfusions for pregnant women with a DIC score of 8 or higher and those with fibrinogen levels of 1.5 g/L or less due to increased maternal death risk.
  • A study involving 595 participants showed that women meeting these criteria had significantly higher requirements for various blood products compared to controls.
  • The findings suggest that fibrinogen levels of 1.5 g/L or lower are effective indicators for predicting obstetrical DIC, similar to a DIC score of 8 or higher in the Japanese context.
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The aim of this work was to noninvasively predict fetal lung immaturity with the ultrasonic gray level histogram width (GLHW), a form of clinical tissue characterization. The study included 22 fetuses in which infant respiratory distress syndrome (IRDS) developed post-delivery, and 25 fetuses without IRDS development. Independent receiver operating characteristic (ROC) analysis of fetal lung-to-liver GLHW ratios, fetal weights, gestational ages and the product of GLHW ratios by gestational ages for this cohort indicated that optimal thresholds for these parameters to differentiate immature from mature were 0.

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Aims: This study examined whether analysis of fetal behavioral states by monitoring fetal heart rate and movement using an actocardiogram (ACG), could provide prognostic information related to fetal central nervous system (CNS) lesions.

Methods: The ACG simultaneously records fetal heart rate (FHR) and fetal movement bursts composed of spikes of ultrasonic Doppler signals. Durations of FHR accelerations and fetal movement bursts were measured manually.

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