Serum concentration of oral midazolam as pediatric preanesthetic medication and factors related to the sedation level.

Background: Preanesthetic medication is important to eliminate surgical anxiety in pediatric patients and facilitate their smooth transfer to the operating room. Midazolam is the most commonly used preanesthetic medication. However, it has been reported that the sedative effect varies from patient to patient.

A rare case of infectious keratitis that developed 27-years after radial keratotomy.

Purpose: To report a rare case of bacterial infectious keratitis that developed 27 years after radial keratotomy.

Observations: A 48-year-old female who underwent bilateral radial keratotomy (RK) 27-years previous presented at our department with pain and visual loss in her right eye after being diagnosed with bacterial keratitis by her primary care physician. Slit-lamp examination showed a focus at the deep layer of the cornea, endothelial plaque, and hypopyon.

Steroid-induced rapid recovery from respiratory dysfunction in a patient with myasthenia gravis after spinal anesthesia.

We report an 83-year-old man with myasthenia gravis (MG) who developed respiratory depression after spinal anesthesia for transurethral laser enucleation of the prostate. He became less responsive after complained of dyspnea, with a decrease of SpO to 83% approximately 13 min after intrathecal administration of 0.5% isobaric bupivacaine 3 ml.

The tyrosine kinase inhibitor imatinib [STI571] induces regression of xenografted canine mast cell tumors in SCID mice.

Canine mast cell tumors (MCTs) are the most common cutaneous tumors in the dog. They have a wide range of behaviour, which can make these tumors challenging to treat. Recently, mutations in c-kit proto-oncogene have been identified in several canine MCTs.