Publications by authors named "Mariko Kaji"
The aim of the study was to investigate the relationship between glucose effectiveness (Sg) and some metabolic parameters in male and female young Japanese. We measured plasma glucose and immunoreactive insulin levels in 1309 young Japanese persons (age <40 years) with normal glucose tolerance (NGT) before and at 30, 60, and 120 min during a 75 gram oral glucose tolerance test. We also measured serum adiponectin and high-sensitivity C-reactive protein (hsCRP) levels and oral glucose effectiveness (SgI), and investigated factors related to SgI.
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- * Researchers analyzed 29 OHCA patients, finding that high serum free T4 (F-T4) levels were positively correlated with ROSC, while low serum potassium and cortisol levels were also noteworthy in relation to patient outcomes.
- * The findings suggest that higher F-T4 levels may enhance heart cell responses and improve chances for ROSC, indicating a potential biomarker for prognosis in OHCA patients.
Context: Slight elevations in plasma glucose (PG) manifest in advance of diabetes onset, but abnormalities in immunoreactive insulin (IRI), proinsulin (Pro), and adiponectin dynamics during this stage remain poorly understood.
Objective: The objective of this work is to investigate whether IRI and Pro dynamics become abnormal as glucose tolerance deteriorates from within the normal range toward impaired glucose tolerance (IGT), as well as the relationship between PG, and these dynamics and serum adiponectin levels.
Design: A cross-sectional study was designed.
Article Synopsis
- Body weight loss in morbidly obese patients can improve health issues like diabetes and hypertension, but maintaining that weight loss is challenging.
- A study of 31 hospitalized patients found that those who lost weight more rapidly during their stay had lower initial body weight and fat mass, regardless of their diabetes status.
- Post-hospitalization, patients overall maintained their weight for 3 months, but many gained weight after a year; however, diabetic patients tended to gain less weight compared to non-diabetic patients.
Article Synopsis
- - The study investigated the relationship between ghrelin dynamics (hormone related to hunger) and beta cell function (insulin production) during oral glucose tolerance tests in healthy individuals under 40 years old.
- - Researchers found that specific indicators of insulin sensitivity (like Stumvoll-1 and insulinogenic index) showed significant correlations in nonobese subjects, suggesting that their beta cell function and ghrelin levels change with BMI.
- - The results indicate that higher BMI is linked to increased glucose and insulin levels, while lowering ghrelin dynamics and beta cell function could contribute to insulin resistance and glucose intolerance in obese individuals.
A 38-year-old woman who consulted a local doctor with chief complaints of sudden palpitations, headaches, and chest pain is herein presented. After admission, pheochromocytoma crisis was suspected. Since the patient had a history of acute heart failure and had once survived an episode of cardiac arrest, a rapid decrease in the catecholamine levels was needed.
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- A case study of a 52-year-old woman reveals her struggles with hypertension and diabetes, which worsened over time despite treatment.
- After developing symptoms like headaches and palpitations, imaging studies identified a 4-cm mass in her left adrenal gland linked to elevated catecholamine levels.
- Post-rupture, significant changes were noted in imaging and hormone levels, leading to a diagnosis of pheochromocytoma confirmed by histopathological examination of the resected tumor, which showed signs of hemorrhagic necrosis.
Efficacy of Adalimumab in a Girl with Refractory Intestinal Behcet's Disease.
Case Rep Rheumatol
November 2015
We describe our experience with a juvenile patient who had refractory intestinal Behcet's disease that responded to adalimumab, a fully humanized antibody against soluble TNF-α and its receptor. The patient, a 13-year-old girl, presented with oral aphthous ulcers, vulvar pain, and rashes on the lower extremities. She gradually developed a low-grade fever, abdominal pain, diarrhea, and hematochezia.
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