Publications by authors named "Mariko Higashikawa"
J Oncol Pharm Pract
June 2021
Article Synopsis
- - This study aimed to identify cancer drugs that require monitoring for cardiac dysfunction (CTRCD) and developed a clinical protocol for early detection.
- - Adverse event data from the Japanese Adverse Drug Event Report database were analyzed to select tyrosine kinase inhibitors that, despite lacking serious side-effect descriptions, showed signs of CTRCD.
- - The results demonstrated that applying the developed protocol led to early detection of CTRCD in 24% of patients using Osimertinib, highlighting the effectiveness of the drug identification method in clinical practice.
