Case Report: A Pediatric Case of Familial Mediterranean Fever Concurrent With Autoimmune Hepatitis.

Familial Mediterranean fever (FMF) is a hereditary, autoinflammatory disease that causes recurrent fever, arthritis, and serositis. The diagnosis of FMF is based on the presentation of typical clinical symptoms and the Mediterranean fever gene () test. However, the challenge lies in diagnosing atypical cases.

Anesthesia Experience for Tonsillectomy in a Patient With Hypofibrinogenemia: A Case Report.

A 26-year-old male patient with hypofibrinogenemia was scheduled to undergo tonsillectomy. Hypofibrinogenemia, defined as low plasma fibrinogen (Fbg) concentration, is a type of congenital Fbg deficiency and is a rare coagulopathy. Perioperative replenishment of Fbg is performed during minor surgeries, aimed at maintaining plasma Fbg concentrations of 50 mg/dL.

[Diagnosis and treatment of acute appendicitis in children].

In this review article, we discussed the pathogenesis, pathophysiology, diagnosis and treatment of acute appendicitis in children. Indications for early surgery, the operative methods of laparoscopic appendectomy and the treatment outcome are also presented.

[Remifentanil for awake craniotomy].

We report two cases of awake craniotomy successfully managed using remifentanil. During the intraoperative awake period lasting 2 to 2.5 hours, the infusion of low doses of remifentanil (0.

[Utility of QuantiFERON TB-2G for tuberculosis contact investigations in public health services].

Objective: The objective of the present study was to examine the utility of QuantiFERON TB-2G (QFT) in tuberculosis contact investigations performed by a public health center.

Methods: Adachi City Public Health Center, Tokyo, started using QFT in its laboratory service in June, 2005. The results of QFT, as well as tuberculin skin tests (TSTs) performed in tuberculosis contact investigations in the 10 month period since then were here analyzed.

Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.

Histamine H1-receptor (H1R) antagonists, or antihistamines, often induce sedative side effects when used for the treatment of allergic disorders. This study compared the sedative profiles of the second-generation antihistamines, fexofenadine and cetirizine, using 3 different criteria: subjective sleepiness evaluated by the Stanford Sleepiness Scale, objective psychomotor tests (simple and choice reaction time tests and visual discrimination tests at 4 different exposure durations), and measurement of histamine H1-receptor occupancy (H1RO) in the brain. Subjective sleepiness and psychomotor performance were measured in 20 healthy Japanese volunteers at baseline and 90 min after administration of fexofenadine 120 mg or cetirizine 20 mg in a double-blind, placebo-controlled crossover study.