The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk.

Objective: Current breast cancer risk prediction scores and algorithms can potentially be further improved by including molecular markers. To this end, we studied the association of circulating plasma proteins using Proximity Extension Assay (PEA) with incident breast cancer risk.

Subjects: In this study, we included 1577 women participating in the prospective KARMA mammographic screening cohort.