Publications by authors named "Marika Vousden"
J Clin Pharmacol
October 2010
Article Synopsis
- A study evaluated how different doses of ritonavir affect the pharmacokinetics of bupropion in healthy volunteers, with subjects receiving two doses of ritonavir over a 30-day period.
- High doses of ritonavir (600 mg) significantly decreased bupropion levels by 62-67%, while low doses (100 mg) resulted in a smaller decrease of 21-22%.
- The findings suggest that when taking ritonavir, bupropion dosage may need adjustment, especially at higher ritonavir doses, but the maximum daily dose of bupropion should not be exceeded.
