Publications by authors named "Marika Svrckova"

The acclimation of higher plants to different light intensities is associated with a reorganization of the photosynthetic apparatus. These modifications, namely, changes in the amount of peripheral antenna (LHCII) of photosystem (PS) II and changes in PSII/PSI stoichiometry, typically lead to an altered chlorophyll (Chl) a/b ratio. However, our previous studies show that in spruce, this ratio is not affected by changes in growth light intensity.

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Myricetin (MYR) and dihydromyricetin (DHM) are classified as natural flavonoids. Both substances are known for their anti-inflammatory and antioxidant properties. In this study, an in vitro model of inflammation was demonstrated on monolayers of scratched fibroblasts or keratinocytes exposed to LPS from Pseudomonas aeruginosa for six hours.

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Human serum albumin (HSA) is a multifunctional protein with ligand binding, transporting and buffering properties. Posttranslational modifications and ligand binding processes are closely related to albumin final functional status. In the last few decades, HSA has been characterized using a broad spectrum of methods, but quantitative data on the HSA's modifications among individuals have not been reported.

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Article Synopsis
  • Proteins can be modified by reactive species, leading to the formation of adducts that can affect their function, specifically noting that methylglyoxal (MGO) binds to and inhibits the enzyme Na/K-ATPase (NKA).
  • MGO primarily modifies NKA's amino acid residues, notably arginine, and forms advanced glycation end-products, impacting the enzyme's activity in both soluble forms and within lipid bilayers.
  • The findings were derived from analyzing NKA from pig kidney and showed that while the α-subunit can be naturally modified by MGO, the β-subunit requires artificial modification; the presence of a glycation suppressor, aminoguanidine, could mitigate MGO's inhibitory effects on
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