Publications by authors named "Marijn J Hollander"
Angew Chem Int Ed Engl
October 2019
Article Synopsis
- Systems chemistry focuses on recreating the complex functions of living systems through chemical reaction networks with specific dynamic behaviors.
- The study introduces reversible, cleavable peptide inhibitors to connect proteolytic enzymatic activity into basic network structures.
- As a demonstration, various mechanisms were explored, including auto-activation leading to sigmoidal enzymatic responses and designing cascades with innovative phosphorylated peptides that can be activated by phosphatases.
